Livin in synergy with Ras induces and sustains corticosteroid resistance in the airway mucosa - Xue, Jin-Mei; An, Yun-Fang; Suo, Li-Min; Mo, Li-Hua; Yang, Gui; Luo, Xiang-Qian; Liu, Da-Bo; Zhao, Chang-Qing; Yang, Ping-Chang (International journal of biological sciences, 2021)
Keywords: Adaptor Proteins, Signal Transducing - metabolism; Adrenal Cortex Hormones - pharmacology; Allergic rhinitis; Allergies; Animals; Antigens; Apoptosis; Asthma; Caspase Inhibitors - pharmacology; Corticoids; Corticosteroids; Cytokines - metabolism; Depletion; Disease; Drug Discovery; Drug Resistance; Eosinophils; Epithelial cells; Epithelium; Gene Expression Profiling - methods; Gene sequencing; Genes; Glucocorticoids; Human subjects; Humans; Hypersensitivity; Inflammatory diseases; Inhibitor of Apoptosis Proteins - metabolism; Leukocytes (eosinophilic); Leukocytes (neutrophilic); Medical imaging; Mice; Mucosa; Nasal Mucosa - metabolism; Nasal Polyps - metabolism; Nasal Polyps - pathology; Nasal Polyps - surgery; Neoplasm Proteins - metabolism; Normal distribution; Patients; Polyps; ras Proteins - metabolism; Research Paper; Respiratory tract; Rhinitis; Rhinitis, Allergic - drug therapy; Rhinitis, Allergic - metabolism; Rhinitis, Allergic - pathology; Sequence Analysis, RNA - methods; Skin; Steroid hormones; Steroids; Thymic stromal lymphopoietin; Thymus; nasal mucosa; glucocorticoid receptor; epithelial cell; inflammation; corticosteroid resistance; livin