Clozapine prescribing barriers in the management of treatment-resistant schizophrenia: A systematic review

• Published in: Medicine (Baltimore) Vol. 100; no. 45; p. e27694
• Main Authors: Baig, Anum Iqbal, Bazargan-Hejazi, Shahrzad, Ebrahim, Gul, Rodriguez-Lara, Jaziel
• Format: Journal Article
• Language: English
• Published: United States Lippincott Williams & Wilkins 12.11.2021
• Subjects: Antipsychotic Agents - therapeutic use; Clozapine - therapeutic use; Delivery of Health Care; Humans; Schizophrenia - drug therapy; Systematic Review and Meta-Analysis

Treatment-resistant schizophrenia is prevalent and difficult to manage, as patients fail multiple antipsychotic trials before being considered as treatment-resistant. Currently clozapine is the only Food and Drug Administration-approved pharmacotherapy for treatment-resistant schizophrenia but remai...