Anticancer Activity of Stilbene‐Based Derivatives

• Published in: ChemMedChem Vol. 12; no. 8; pp. 558 - 570
• Main Authors: De Filippis, Barbara, Ammazzalorso, Alessandra, Fantacuzzi, Marialuigia, Giampietro, Letizia, Maccallini, Cristina, Amoroso, Rosa
• Format: Journal Article
• Language: English
• Published: Germany Wiley Subscription Services, Inc 20.04.2017
• Subjects: Angiogenesis Inhibitors - chemistry; Angiogenesis Inhibitors - pharmacology; anticancer agents; Antineoplastic Agents - chemistry; Antineoplastic Agents - pharmacology; antiproliferation; Apoptosis - drug effects; Berries; Bioavailability; Cancer; Cell Line, Tumor; Cyclooxygenase 2 Inhibitors - chemistry; Cyclooxygenase 2 Inhibitors - pharmacology; Humans; Isomerism; resveratrol; stilbene analogues; Stilbenes - chemistry; Stilbenes - pharmacology; Structure-Activity Relationship; stilbene analogues; antiproliferation; resveratrol; anticancer agents

Stilbene is an abundant structural scaffold in nature, and stilbene‐based compounds have been widely reported for their biological activity. Notably, (E)‐resveratrol and its natural stilbene‐containing derivatives have been extensively investigated as cardioprotective, potent antioxidant, anti‐infla...