Promoting Cardiomyogenesis of hBMSC with a Forming Self‐Assembly hBMSC Microtissues/HA‐GRGD/SF‐PCL Cardiac Patch Is Mediated by the Synergistic Functions of HA‐GRGD

• Published in: Macromolecular bioscience Vol. 17; no. 3; pp. np - n/a
• Main Authors: Chung, Tze‐Wen, Lo, Hsin‐Yu, Chou, Tzung‐Han, Chen, Jan‐Hou, Wang, Shoei‐Shen
• Format: Journal Article
• Language: English
• Published: Germany Wiley Subscription Services, Inc 01.03.2017
• Subjects: Actins - metabolism; Biocompatible Materials; Bone marrow; Bone Marrow Cells - cytology; Caproates - chemistry; cardiac tissue engineering; cardiomyogenesis; Cell Differentiation - genetics; Cell Proliferation - genetics; Fibroins - chemistry; GRGD; hBMSC microtissues/patch; Humans; hyaluronic acid; Hyaluronic Acid - chemistry; Lactones - chemistry; Mesenchymal Stromal Cells - cytology; Myocardial Infarction - pathology; Myocardial Infarction - therapy; Myocytes, Cardiac - cytology; Silk - chemistry; Stem cells; Tetrazolium Salts - chemistry; Thiazoles - chemistry; Tissue Culture Techniques; Tissue Engineering; Tissue Scaffolds; hBMSC microtissues/patch; GRGD; cardiac tissue engineering; cardiomyogenesis; hyaluronic acid

Bone marrow‐derived mesenchymal stem cell microtissues (BMSCMT) enhanced cardiomyogenesis in vitro and cardiac repairs of myocardial infarcted hearts in vivo are documented. Producing human BMSCMT onto patches in vitro for cardiac tissue engineering has not been reported. For possibly producing huma...