An effective and validated prognostic model for uterine corpus endometrial cancer based on gene main effects and gene-gene interactions

• Published in: Medicine (Baltimore) Vol. 104; no. 23; p. e42583
• Main Authors: Han, Yujing, Huang, Yingqin, Luo, Deyi
• Format: Journal Article
• Language: English
• Published: Hagerstown, MD Lippincott Williams & Wilkins 06.06.2025
• Subjects: Aged; Endometrial Neoplasms - genetics; Endometrial Neoplasms - mortality; Female; Gene Expression Profiling; Humans; Middle Aged; Observational Study; Prognosis; Risk Assessment - methods; ROC Curve; Transcriptome; gene main effects; prognostic model; uterine corpus endometrial cancer; gene-gene interactions; gene–gene interactions

Uterine corpus endometrial carcinoma (UCEC) poses a significant to women's health. Accurate prediction of prognosis plays a crucial role in facilitating clinical decision-making processes. Therefore, this study aimed to develop a robust prognostic model based on gene expression profile. Gene ex...