Optimisation of Intervertebral Disc Mechanical Properties and the Impact of Vertebral Alignment in Subject‐Specific Finite Element Models

• Published in: International journal for numerical methods in biomedical engineering Vol. 41; no. 6; pp. e70052 - n/a
• Main Authors: Kelly, Emily S., Javadi, Akbar A., Holsgrove, Timothy P., Ward, Michael, Williams, David, Williams, Jenny, Holt, Cathy, Meakin, Judith R.
• Format: Journal Article
• Language: English
• Published: Hoboken, USA John Wiley & Sons, Inc 01.06.2025; Wiley Subscription Services, Inc
• Subjects: Alignment; Animals; Axial compression; Basic Research; Biomechanical Phenomena; Boundary conditions; Finite Element Analysis; Finite element method; finite element modelling; Humans; In vitro methods and tests; Intervertebral Disc - physiology; intervertebral disc properties; Intervertebral discs; lumbar spine; Lumbar Vertebrae - physiology; Mathematical models; Mechanical properties; Models, Biological; Optimization; Segments; Spine; Spine (lumbar); Stiffness matrix; Stress, Mechanical; subject‐specific modelling; Swine; Vertebrae; Weight-Bearing; finite element modelling; intervertebral disc properties; lumbar spine; subject‐specific modelling

ABSTRACT Subject‐specific finite element models could improve understanding of how spinal loading varies between people, based on differences in morphology and tissue properties. However, determining accurate subject‐specific intervertebral disc (IVD) properties can be difficult due to the spine...