Xpert MTB/RIF Assay Shortens Airborne Isolation for Hospitalized Patients With Presumptive Tuberculosis in the United States

• Published in: Clinical infectious diseases Vol. 59; no. 2; pp. 186 - 192
• Main Authors: Lippincott, Christopher K., Miller, Melissa B., Popowitch, Elena B., Hanrahan, Colleen F., Van Rie, Annelies
• Format: Journal Article
• Language: English
• Published: Oxford OXFORD UNIVERSITY PRESS 15.07.2014; Oxford University Press
• Subjects: Adolescent; Adult; Aged; Aged, 80 and over; and Commentaries; ARTICLES AND COMMENTARIES; Bacterial diseases; Bacteriological Techniques - methods; Biological and medical sciences; Cohort Studies; Cutaneous tuberculosis; Database design; Disease control; Epidemiology; Female; Hospitalization; Human bacterial diseases; Humans; Infectious diseases; Latent tuberculosis; Male; Medical sciences; Medical treatment; Microscopy; Microscopy - methods; Middle Aged; Molecular Diagnostic Techniques - methods; Mycobacterium tuberculosis; Mycobacterium tuberculosis - isolation & purification; Patient Isolation; Pulmonary tuberculosis; Sensitivity and Specificity; Specimens; Sputum; Sputum - microbiology; Time Factors; Tuberculosis; Tuberculosis and atypical mycobacterial infections; Tuberculosis, Pulmonary - diagnosis; United States; Young Adult; United States; North America; America; United States > US; Infection; Human; Tuberculosis; Bacteriosis; Isolation; Hospitalization; Mycobacterial infection; infection control; Xpert; United States; tuberculosis

Background. In the United States, individuals with presumptive pulmonary tuberculosis are placed in airborne infection isolation (AII) and assessed by smear microscopy on 3 respiratory specimens collected 8–24 hours apart. Xpert MTB/RIF assay (Xpert) on 1, 2, or 3 specimens may be more efficient for...