Rhodamines NN: A Novel Class of Caged Fluorescent Dyes

A bright future: The reaction of diazomethane with acid chlorides obtained from N,N,N′,N′‐tetraalkylrhodamines affords 2‐diazo‐2,3‐dihydro‐1H‐indenespiro[1,9′]‐9H‐xanthen‐3‐ones—a novel class of caged rhodamines. These dyes allow new imaging procedures based on the step‐wise activation and detection...

Full description

Saved in:
Bibliographic Details
Published inAngewandte Chemie (International ed.) Vol. 49; no. 20; pp. 3520 - 3523
Main Authors Belov, Vladimir N, Wurm, Christian A, Boyarskiy, Vadim P, Jakobs, Stefan, Hell, Stefan W
Format Journal Article
LanguageEnglish
Published Weinheim Wiley-VCH Verlag 03.05.2010
WILEY-VCH Verlag
WILEY‐VCH Verlag
Wiley
Subjects
caged compounds
Chemistry
Chemistry, Multidisciplinary
diazo compounds
fluorescence
Fluorescent Dyes - chemical synthesis
Fluorescent Dyes - chemistry
imaging agents
Molecular Structure
Physical Sciences
rhodamines
Rhodamines - chemical synthesis
Rhodamines - chemistry
Science & Technology
Spectrophotometry
rhodamines
CROSS-SECTIONS
FLUOROPHORES
PHOTOCHROMISM
imaging agents
RELEASE
MICROSCOPY
fluorescence
caged compounds
NANOSCOPY
PHOTOLABILE PROTECTING GROUPS
PHOTOACTIVATION
diazo compounds
PROTEINS
Online AccessGet full text

Cover

More Information
Summary:A bright future: The reaction of diazomethane with acid chlorides obtained from N,N,N′,N′‐tetraalkylrhodamines affords 2‐diazo‐2,3‐dihydro‐1H‐indenespiro[1,9′]‐9H‐xanthen‐3‐ones—a novel class of caged rhodamines. These dyes allow new imaging procedures based on the step‐wise activation and detection of several fluorescent markers (see picture).
Bibliography:http://dx.doi.org/10.1002/anie.201000150
This work was supported by the Leibniz Prize fund of the DFG (to SWH) and the Max-Planck-Gesellschaft. We are grateful to Donald Ouw (MPI), Reinhard Machinek, Dr. Holm Frauendorf, and their co-workers (Institut für Organische und Biomolekulare Chemie, Georg-August-Universität Göttingen) for recording spectra.
istex:3B11E50D0276843C8FDD6426720D87A584826407
DFG
ark:/67375/WNG-H65FP29M-Q
ArticleID:ANIE201000150
Max-Planck-Gesellschaft
This work was supported by the Leibniz Prize fund of the DFG (to SWH) and the Max‐Planck‐Gesellschaft. We are grateful to Donald Ouw (MPI), Reinhard Machinek, Dr. Holm Frauendorf, and their co‐workers (Institut für Organische und Biomolekulare Chemie, Georg‐August‐Universität Göttingen) for recording spectra.
ObjectType-Article-1
SourceType-Scholarly Journals-1
ObjectType-Feature-2
content type line 23
ISSN:1433-7851
1521-3773
DOI:10.1002/anie.201000150