Chemical structural and chain conformational characterization of some bioactive polysaccharides isolated from natural sources

Some polysaccharides isolated from natural sources show various important biological activities, such as antitumor, immunomodulatory, and anti-inflammatory effects, which are strongly affected by their chemical structures and chain conformations. This article attempts to review the current developme...

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Published inCarbohydrate polymers Vol. 76; no. 3; pp. 349 - 361
Main Authors Yang, Liqun, Zhang, Li-Ming
Format Journal Article
LanguageEnglish
Published Kidlington Elsevier Ltd 09.04.2009
Elsevier
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Abstract Some polysaccharides isolated from natural sources show various important biological activities, such as antitumor, immunomodulatory, and anti-inflammatory effects, which are strongly affected by their chemical structures and chain conformations. This article attempts to review the current development on structural and conformational characterization of some importantly bioactive polysaccharides isolated from natural sources. The chemical structures were analyzed by FTIR, liquid-state NMR (one and two dimensions), solid-sate NMR, Raman spectroscopy, gas chromatography (GC), GC–Mass (GC–MS), and high-performance liquid chromatography (HPLC). The chain conformations of polysaccharides in solutions were investigated using static and dynamic light scattering, viscosity analysis based on the theory of dilute polymer solution, circular dichroism analysis, atomic force microscopy (AFM) including single molecular AFM and AFM-based single-molecule force spectroscopy, fluorescence correlation spectroscopy and NMR spectroscopy.
AbstractList Some polysaccharides isolated from natural sources show various important biological activities, such as antitumor, immunomodulatory, and anti-inflammatory effects, which are strongly affected by their chemical structures and chain conformations. This article attempts to review the current development on structural and conformational characterization of some importantly bioactive polysaccharides isolated from natural sources. The chemical structures were analyzed by FTIR, liquid-state NMR (one and two dimensions), solid-sate NMR, Raman spectroscopy, gas chromatography (GC), GC–Mass (GC–MS), and high-performance liquid chromatography (HPLC). The chain conformations of polysaccharides in solutions were investigated using static and dynamic light scattering, viscosity analysis based on the theory of dilute polymer solution, circular dichroism analysis, atomic force microscopy (AFM) including single molecular AFM and AFM-based single-molecule force spectroscopy, fluorescence correlation spectroscopy and NMR spectroscopy.
Author Yang, Liqun
Zhang, Li-Ming
Author_xml – sequence: 1
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  fullname: Yang, Liqun
  email: yanglq@mail.sysu.edu.cn
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  givenname: Li-Ming
  surname: Zhang
  fullname: Zhang, Li-Ming
BackLink http://pascal-francis.inist.fr/vibad/index.php?action=getRecordDetail&idt=21397965$$DView record in Pascal Francis
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Issue 3
Keywords Chain conformation
Polysaccharides
Biological activity
Chemical structure
Chemical solution
Molecular structure
Plant origin
Bioactive material
Oside polymer
Review
Conformation
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Snippet Some polysaccharides isolated from natural sources show various important biological activities, such as antitumor, immunomodulatory, and anti-inflammatory...
SourceID pascalfrancis
crossref
elsevier
SourceType Index Database
Enrichment Source
Publisher
StartPage 349
SubjectTerms Applied sciences
Biological activity
Chain conformation
Chemical structure
Exact sciences and technology
Natural polymers
Physicochemistry of polymers
Polysaccharides
Starch and polysaccharides
Title Chemical structural and chain conformational characterization of some bioactive polysaccharides isolated from natural sources
URI https://dx.doi.org/10.1016/j.carbpol.2008.12.015
Volume 76
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