Quantification of serum HBXAP DNA in lung cancer patients by quantitative fluorescent polymerase chain reaction

• Published in: Molecular biology reports Vol. 40; no. 6; pp. 4091 - 4096
• Main Authors: Hou, Yu-Lei, Chen, Hui, Ge, Ming-Jian, Li, Feng-Zeng, Xue, Cheng-Jun, Wu, Yan-Feng, Luo, Hai-Xia
• Format: Journal Article
• Language: English
• Published: Dordrecht Springer Netherlands 01.06.2013; Springer Nature B.V
• Subjects: Adult; Aged; Animal Anatomy; Animal Biochemistry; Biomarkers, Tumor - blood; Biomedical and Life Sciences; Case-Control Studies; Deoxyribonucleic acid; DNA; DNA, Neoplasm - blood; Female; Fluorescence; Hepatitis B virus; Histology; Humans; Life Sciences; Lung cancer; Lung Neoplasms - blood; Lung Neoplasms - diagnosis; Lung Neoplasms - genetics; Male; Middle Aged; Morphology; Nuclear Proteins - genetics; Patients; Polymerase chain reaction; Polymerase Chain Reaction - methods; ROC Curve; Trans-Activators - genetics; Hepatitis B virus x associated protein; Diagnostic efficacy; Lung cancer; Circulating DNA

Hepatitis B virus x associated protein ( HBXAP ), as a subunit of chromatin remodeling and spacing factor, plays a critical role in cancer development through gene amplification. In this study, we aimed to quantify the levels of serum HBXAP DNA, to analyze and compare its diagnostic value with exist...