LncRNA XIST facilitates the odontogenic differentiation of dental pulp stem cells via the FUS/ZBTB16

• Published in: Journal of applied oral science Vol. 32; p. e20230444
• Main Authors: CHENG, Ruiqing, SUN, Honglei, QIAO, Xiaotong, CHEN, Xuefang
• Format: Journal Article
• Language: English
• Published: Brazil Faculdade De Odontologia De Bauru - USP 01.01.2024; University of São Paulo
• Subjects: Blotting, Western; Cell Differentiation - genetics; Cell Differentiation - physiology; Cells, Cultured; Dental Pulp - cytology; Dental pulp stem cells; DENTISTRY, ORAL SURGERY & MEDICINE; Extracellular Matrix Proteins; Flow Cytometry; FUS; Humans; LncRNA XIST; Odontogenesis - genetics; Odontogenesis - physiology; Odontogenic differentiation; Phosphoproteins; Promyelocytic Leukemia Zinc Finger Protein; Real-Time Polymerase Chain Reaction; Reproducibility of Results; RNA, Long Noncoding - genetics; RNA, Long Noncoding - metabolism; RNA, Long Noncoding - physiology; RNA-Binding Protein FUS - genetics; RNA-Binding Protein FUS - metabolism; RNA-Binding Protein FUS - physiology; Stem Cells - cytology; Stem Cells - physiology; ZBTB16; FUS; Dental pulp stem cells; LncRNA XIST; ZBTB16; Odontogenic differentiation

This study aims to explore the regulatory mechanism of long noncoding RNA X inactive specific transcript (lncRNA XIST) in the odontogenic differentiation of human dental pulp stem cells (hDPSCs). hDPSCs were obtained from freshly extracted third molars and identified by flow cytometry. Odontogenic d...