Response mode-dependent differences in neurofunctional networks during response inhibition: an EEG-beamforming study

• Published in: Brain Structure and Function Vol. 221; no. 8; pp. 4091 - 4101
• Main Authors: Dippel, Gabriel, Chmielewski, Witold, Mückschel, Moritz, Beste, Christian
• Format: Journal Article
• Language: English
• Published: Berlin/Heidelberg Springer Berlin Heidelberg 01.11.2016; Springer Nature B.V
• Subjects: Adult; Attention - physiology; Biomedical and Life Sciences; Biomedicine; Cell Biology; Cerebral Cortex - physiology; Cognition & reasoning; Electroencephalography; Executive Function - physiology; Female; Humans; Impulsive Behavior - physiology; Inhibition (Psychology); Male; Neurology; Neuropsychological Tests; Neurosciences; Original Article; Psychomotor Performance; Signal Processing, Computer-Assisted; Theta Rhythm; Young Adult; Theta frequency; Beamforming; Response inhibition; Temporo-parietal junction; EEG
• ISSN: 1863-2653; 1863-2661; 1863-2661; 0340-2061
• DOI: 10.1007/s00429-015-1148-y

Response inhibition processes are one of the most important executive control functions and have been subject to intense research in cognitive neuroscience. However, knowledge on the neurophysiology and functional neuroanatomy on response inhibition is biased because studies usually employ experimental paradigms (e.g., sustained attention to response task, SART) in which behavior is susceptible to impulsive errors. Here, we investigate whether there are differences in neurophysiological mechanisms and networks depending on the response mode that predominates behavior in a response inhibition task. We do so comparing a SART with a traditionally formatted task paradigm. We use EEG-beamforming in two tasks inducing opposite response modes during action selection. We focus on theta frequency modulations, since these are implicated in cognitive control processes. The results show that a response mode that is susceptible to impulsive errors (response mode used in the SART) is associated with stronger theta band activity in the left temporo-parietal junction. The results suggest that the response modes applied during response inhibition differ in the encoding of surprise signals, or related processes of attentional sampling. Response modes during response inhibition seem to differ in processes necessary to update task representations relevant to behavioral control.