Functional UDP-glucuronyltransferase 2B15 polymorphism and bisphenol A concentrations in blood: results from physiologically based kinetic modelling - Partosch, Falko; Mielke, Hans; Gundert-Remy, Ursula (Archives of toxicology, 2013)
Keywords: Area Under Curve; Benzhydryl Compounds - blood; Benzhydryl Compounds - pharmacokinetics; Biological Availability; Biomedical and Life Sciences; Biomedicine; Biotransformation; Bisphenol A; Blood; Endocrine Disruptors - blood; Endocrine Disruptors - pharmacokinetics; Environmental Health; Enzymes; Genotype; Glucuronosyltransferase - genetics; Glucuronosyltransferase - metabolism; Half-Life; Humans; Metabolic Clearance Rate; Metabolism; Models, Biological; Occupational Medicine/Industrial Medicine; Pharmacogenetics; Pharmacology/Toxicology; Phenols - blood; Phenols - pharmacokinetics; Phenotype; Polymorphism; Polymorphism, Genetic; Risk Assessment; Toxicokinetics and Metabolism; Toxicology; Bisphenol A; Physiologically based kinetic modelling; Systemic availability; Risk assessment; Polymorphically expressed UGT2B15 metabolism; Internal exposure