A rapid method for detection of putative RNAi target genes in genomic data

• Published in: Bioinformatics Vol. 19; no. suppl-2; pp. ii73 - ii80
• Main Authors: Horesh, Yair, Amir, Amihood, Michaeli, Shulamit, Unger, Ron
• Format: Journal Article
• Language: English
• Published: England Oxford University Press 27.09.2003; Oxford Publishing Limited (England)
• Subjects: Animals; Base Sequence; Caenorhabditis - genetics; Caenorhabditis briggsae; Caenorhabditis elegans; Chromosome Mapping - methods; Databases, Genetic; Gene Targeting - methods; Immune response; Molecular Sequence Data; RNA Interference; RNA, Small Interfering - genetics; Sequence Analysis, RNA - methods

RNAi, inhibition of gene expression by double stranded RNA molecules, has rapidly become a powerful laboratory technique to study gene function. The effectiveness of the procedure raised the question of whether this laboratory technique may actually mimic a natural cellular control mechanism that wo...