Necrotizing Enterocolitis Associated with Clostridium perfringens Type A in Previously Healthy North American Adults

• Published in: Journal of the American College of Surgeons Vol. 201; no. 1; pp. 48 - 56
• Main Authors: Sobel, Jeremy, Mixter, Charles G., Kolhe, Priti, Gupta, Amita, Guarner, Jeannette, Zaki, Sherif, Hoffman, Neil A., Songer, J. Glenn, Fremont-Smith, Maurice, Fischer, Marc, Killgore, George, Britz, Phyllis H., MacDonald, Clifford
• Format: Journal Article
• Language: English
• Published: New York, NY Elsevier Inc 01.07.2005; Elsevier Science
• Subjects: Adult; Biological and medical sciences; Clostridium Infections - diagnosis; Clostridium perfringens - classification; Clostridium perfringens - isolation & purification; Enterocolitis, Necrotizing - microbiology; Fatal Outcome; Gastroenterology. Liver. Pancreas. Abdomen; General aspects; Humans; Intestinal Mucosa - blood supply; Ischemia - etiology; Male; Medical sciences; Mesenteric Vascular Occlusion - etiology; Mesenteric Veins - pathology; Middle Aged; Necrosis; Other diseases. Semiology; Portal Vein - pathology; Stomach. Duodenum. Small intestine. Colon. Rectum. Anus; Venous Thrombosis - etiology; North America; America; ANEC; IHC; ER; PCR; Human; Healthy subject; Clostridiales; Necrotizing enterocolitis; Clostridium perfringens; Medicine; Association; Newborn; Treatment; Surgery; Clostridiaceae; Digestive diseases; Bacteria; Intestinal disease; Adult

Necrotizing enteritis associated with Clostridium perfringens type C (“pigbel”) is a well-known syndrome in severely protein-deprived populations in the Pacific. It is exceedingly rare in the developed world. C perfringens type A is a common cause of acute gastroenteritis and, in a handful of infect...