The Effect of Regular Colchicine Treatment on Biomarkers Related with Vascular Injury in Newly Diagnosed Patients with Familial Mediterranean Fever

• Published in: Inflammation Vol. 35; no. 3; pp. 1191 - 1197
• Main Authors: Sari, Ismail, Yuksel, Arif, Kozaci, Didem, Selcuk, Sema, Gokce, Goksel, Yildiz, Yasar, Demirel, Hakan, Sop, Gulten, Alacacioglu, Ahmet, Gunay, Necati, Akkoc, Nurullah
• Format: Journal Article
• Language: English
• Published: Boston Springer US 01.06.2012; Springer Nature B.V
• Subjects: Adult; alpha-2-HS-Glycoprotein - analysis; Biomarkers - blood; Biomedical and Life Sciences; Biomedicine; C-Reactive Protein - analysis; CD146 Antigen - blood; Colchicine - pharmacology; Colchicine - therapeutic use; Familial Mediterranean Fever - diagnosis; Familial Mediterranean Fever - drug therapy; Female; Humans; Immunology; Intercellular Adhesion Molecule-1 - blood; Internal Medicine; Male; Pathology; Pharmacology/Toxicology; Plasminogen Activator Inhibitor 1 - blood; Rheumatology; Vascular System Injuries - drug therapy; cell adhesion molecules; melanoma cell adhesion molecule; familial Mediterranean fever; inflammation; plasminogen activator inhibitor-1 and human fetuin-A; intercellular adhesion molecule-1

We aimed to evaluate some of the vascular biomarkers in newly diagnosed, colchicine naive familial Mediterranean fever (FMF) patients. Our primary aim was to investigate the effect of regular colchicine treatment on these variables. Twenty-four (12 males [M] and 12 females [F], 33.3 ± 13.4 years) ne...