IL-6 AND SOLUBLE IL-6 RECEPTOR LEVELS CHANGE DIFFERENTLY AFTER SURGERY BOTH IN THE BLOOD AND IN THE OPERATIVE FIELD

• Published in: Cytokine (Philadelphia, Pa.) Vol. 9; no. 6; pp. 447 - 452
• Main Authors: Hisano, Saburo, Sakamoto, Kiyoshi, Ishiko, Takatoshi, Kamohara, Hidenobu, Ogawa, Michio
• Format: Journal Article
• Language: English
• Published: England Elsevier Ltd 01.06.1997
• Subjects: Aged; Antigens, CD - blood; Antigens, CD - metabolism; Body Fluids - immunology; Enzyme-Linked Immunosorbent Assay; Female; Humans; IL-6; Interleukin-6 - blood; Interleukin-6 - metabolism; Kinetics; Male; Middle Aged; Postoperative Complications - blood; Postoperative Complications - immunology; Receptors, Interleukin - blood; Receptors, Interleukin - metabolism; Receptors, Interleukin-6; soluble IL-6 receptor; Stress, Physiological - blood; Stress, Physiological - immunology; surgery; trauma; trauma; soluble IL-6 receptor; IL-6; surgery

To investigate alterations in post-operative levels of IL-6 and soluble IL-6 and soluble IL-6 receptor (sIL-6R), we examined their levels in serum and samples of drainage fluids from 26 patients who underwent thoracoabdominal surgery. Serum IL-6 levels reached the maximum within the first post-opera...