Late-onset disease is associated with a mild phenotype in children with familial Mediterranean fever

• Published in: Clinical rheumatology Vol. 35; no. 7; pp. 1837 - 1840
• Main Authors: Özdel, Semanur, Özçakar, Z.Birsin, Kunt, Seda Şahin, Elhan, Atilla H., Yalçınkaya, Fatoş
• Format: Journal Article
• Language: English
• Published: London Springer London 01.07.2016; Springer Nature B.V
• Subjects: Adolescent; Child; Colchicine - therapeutic use; Familial Mediterranean Fever - drug therapy; Familial Mediterranean Fever - genetics; Female; Homozygote; Humans; Late Onset Disorders - diagnosis; Male; Medicine; Medicine & Public Health; Mutation; Original Article; Pediatrics; Phenotype; Pyrin - genetics; Retrospective Studies; Rheumatology; Severity of Illness Index; Turkey; Disease severity; Paediatric; Familial Mediterranean fever; Late onset

Familial Mediterranean fever (FMF) is an autosomal recessive disease, characterised by recurrent, self-limited attacks of fever with serositis. Recently, it was shown that patients with early disease onset during childhood period had more severe disease. The aim of this study was to describe the dem...