Colonization, safety, and tolerability study of the Streptococcus salivarius 24SMBc nasal spray for its application in upper respiratory tract infections

• Published in: European journal of clinical microbiology & infectious diseases Vol. 34; no. 10; pp. 2075 - 2080
• Main Authors: Santagati, M., Scillato, M., Muscaridola, N., Metoldo, V., La Mantia, I., Stefani, S.
• Format: Journal Article
• Language: English
• Published: Berlin/Heidelberg Springer Berlin Heidelberg 01.10.2015; Springer Nature B.V
• Subjects: Adult; Anti-Bacterial Agents - administration & dosage; Biomedical and Life Sciences; Biomedicine; Colonization; Ear diseases; Female; Humans; Internal Medicine; Male; Medical equipment; Medical Microbiology; Microbiota; Middle Aged; Nasal Sprays; Original Article; Pathogens; Patients; Pilot Projects; Prevention; Probiotics; Probiotics - administration & dosage; Respiratory tract; Respiratory Tract Infections - drug therapy; Safety; Streptococcal Infections - drug therapy; Streptococcus; Streptococcus - drug effects; Streptococcus infections; Streptococcus salivarius; Italy; Moraxella Catarrhalis; Molecular Fingerprinting; Oral Microbiota; Nasal Spray; Recurrent Otitis Medium

Streptococcus salivarius , a non-pathogenic species and the predominant colonizer of the oral microbiota, finds a wide application in the prevention of upper respiratory tract infections, also reducing the frequency of their main pathogens. In this pilot study, the primary objective was to evaluate...