β- and α-Cell Dysfunctions in Africans With Ketosis-Prone Atypical Diabetes During Near-Normoglycemic Remission

• Published in: Diabetes care Vol. 36; no. 1; pp. 118 - 123
• Main Authors: Choukem, Siméon-Pierre, Sobngwi, Eugene, Boudou, Philippe, Fetita, Lila-Sabrina, Porcher, Raphael, Ibrahim, Fidaa, Blondeau, Bertrand, Vexiau, Patrick, Mauvais-Jarvis, Franck, Calvo, Fabien, Gautier, Jean-François
• Format: Journal Article
• Language: English
• Published: Alexandria, VA American Diabetes Association 01.01.2013
• Subjects: Adult; African Continental Ancestry Group; Biological and medical sciences; C-Peptide - blood; Diabetes Mellitus, Type 1 - blood; Diabetes Mellitus, Type 1 - physiopathology; Diabetes. Impaired glucose tolerance; Diabetic Ketoacidosis - blood; Diabetic Ketoacidosis - physiopathology; Endocrine pancreas. Apud cells (diseases); Endocrinopathies; Female; Glucagon - blood; Glucagon-Secreting Cells - physiology; Glucose Tolerance Test; Humans; Insulin - blood; Insulin-Secreting Cells - physiology; Male; Medical sciences; Metabolic diseases; Middle Aged; Miscellaneous; Original Research; Public health. Hygiene; Public health. Hygiene-occupational medicine; Autoimmunity; Endocrinopathy; Human; Nutrition; Metabolic diseases; African; Dysfunction; Remission; Atypical; β Cell; Pancreas; Endocrinology; Ketosis-prone diabetes

Ketosis-prone atypical diabetes (KPD) is a subtype of diabetes in which the pathophysiology is yet to be unraveled. The aim of this study was to characterize β- and α-cell functions in Africans with KPD during remission. We characterized β- and α-cell functions in Africans with KPD during remission....