Does Systemic Sclerosis–associated Interstitial Lung Disease Burn Out? Specific Phenotypes of Disease Progression

• Published in: Annals of the American Thoracic Society Vol. 15; no. 12; pp. 1427 - 1433
• Main Authors: Guler, Sabina A., Winstone, Tiffany A., Murphy, Darra, Hague, Cameron, Soon, Jeanette, Sulaiman, Nada, Li, Kathy H., Dunne, James, Wilcox, Pearce G., Ryerson, Christopher J.
• Format: Journal Article
• Language: English
• Published: United States American Thoracic Society 01.12.2018
• Subjects: Arthritis; Bias; Carbon monoxide; Generalized linear models; Health risk assessment; Lung diseases; Mortality; Physiology; Pulmonary fibrosis; Scleroderma; Short term; Studies; Tomography; phenotype; respiratory function tests; pulmonary fibrosis; systemic scleroderma

Previous studies have suggested that interstitial lung disease (ILD) progresses most rapidly early in the course of systemic sclerosis-associated (SSc)-ILD, and that SSc-ILD is often more stable or even "burned out" after the first 4 years following diagnosis. Our objectives were to determ...