Age-Related Changes in Risky Decision Making and Associated Neural Circuitry in a Rat Model

• Published in: eNeuro Vol. 10; no. 1; p. ENEURO.0385-22.2022
• Main Authors: Orsini, Caitlin A, Pyon, Wonn S, Dragone, Richard J, Faraji, Mojdeh, Wheeler, Alexa-Rae, Pompilus, Marjory, Febo, Marcelo, Bizon, Jennifer L, Setlow, Barry
• Format: Journal Article
• Language: English
• Published: United States Society for Neuroscience 01.01.2023
• Subjects: Aged; Animals; Basolateral Nuclear Complex; Brain - diagnostic imaging; Decision Making; Humans; Male; New Research; Prefrontal Cortex; Quality of Life; Rats; Reward; Risk-Taking; Young Adult; risk taking; punishment; aging; rat; decision making; neuroimaging

Altered decision making at advanced ages can have a significant impact on an individual's quality of life and the ability to maintain personal independence. Relative to young adults, older adults make less impulsive and less risky choices; although these changes in decision making could be cons...