Effect of intravenous zoledronic acid infusion on electrocardiographic parameters in patients with osteoporosis

• Published in: Osteoporosis international Vol. 27; no. 12; pp. 3543 - 3547
• Main Authors: Aktas, I., Nazikoglu, C., Kepez, A., Ozkan, F. U., Kaysin, M. Y., Akpinar, P., Dogan, Z., Ileri, C., Saymaz, S., Erdogan, O.
• Format: Journal Article
• Language: English
• Published: London Springer London 01.12.2016; Springer Nature B.V
• Subjects: Aged; Aged, 80 and over; Arrhythmias, Cardiac - epidemiology; Atrial Fibrillation - epidemiology; Bone Density Conservation Agents - administration & dosage; Bone Density Conservation Agents - adverse effects; Cardiac arrhythmia; Diphosphonates - administration & dosage; Diphosphonates - adverse effects; EKG; Electrocardiography; Endocrinology; Female; Fibrillation; Humans; Imidazoles - administration & dosage; Imidazoles - adverse effects; Intravenous administration; Male; Medicine; Medicine & Public Health; Original Article; Orthopedics; Osteoporosis; Osteoporosis - drug therapy; Population studies; Rheumatology; Ventricle; Zoledronic acid; P wave dispersion; Zoledronic acid; Cardiac arrhythmia; Atrial fibrillation; QT dispersion

Summary We evaluated the effects of zoledronic acid (ZA) therapy on electrocardiographic (ECG) parameters for the first time in the literature. Measurements were performed on ECGs obtained before and after ZA infusion on the same day as well as 1 month after the infusion. ZA infusion did not have an...