A unique fatal case of Waterhouse–Friderichsen syndrome caused by Proteus mirabilis in an immunocompetent subject: Case report and literature analysis

• Published in: Medicine (Baltimore) Vol. 98; no. 34; p. e16664
• Main Authors: Ventura Spagnolo, Elvira, Mondello, Cristina, Roccuzzo, Salvatore, Stassi, Chiara, Cardia, Luigi, Grieco, Angela, Raffino, Cataldo
• Format: Journal Article
• Language: English
• Published: United States the Author(s). Published by Wolters Kluwer Health, Inc 01.08.2019; Wolters Kluwer Health
• Subjects: Adult; Clinical Case Report; Humans; Immunocompromised Host; Male; Proteus Infections - complications; Proteus mirabilis; Waterhouse-Friderichsen Syndrome - etiology

The Waterhouse-Friderichsen syndrome (WFS), also known as purpura fulminans, is a potentially lethal condition described as acute hemorrhagic necrosis of the adrenal glands. It is often caused by infection. Classically, Neisseriae meningitidis represents the main microorganism related to WFS, althou...