Autologous Pancreatic Islet Cell Transplantation Following Pancreatectomy for Pancreas Diseases Other Than Chronic Pancreatitis: A 15-y Study of the Milan Protocol

• Published in: Transplantation Vol. 108; no. 9; p. 1962
• Main Authors: Piemonti, Lorenzo, Melzi, Raffella, Aleotti, Francesca, Capretti, Giovanni, Nano, Rita, Mercalli, Alessia, Magistretti, Paola, Caldara, Rossana, Pecorelli, Nicolò, Catarinella, Davide, Gremizzi, Chiara, Gavazzi, Francesca, De Cobelli, Francesco, Poretti, Dario, Falconi, Massimo, Zerbi, Alessandro, Balzano, Gianpaolo
• Format: Journal Article
• Language: English
• Published: United States 01.09.2024
• Subjects: Adult; Aged; Diabetes Mellitus - epidemiology; Diabetes Mellitus - etiology; Feasibility Studies; Female; Humans; Islets of Langerhans Transplantation - adverse effects; Islets of Langerhans Transplantation - methods; Male; Middle Aged; Pancreatectomy - adverse effects; Pancreatic Diseases - surgery; Pancreatitis, Chronic - surgery; Transplantation, Autologous; Treatment Outcome

Pancreatogenic diabetes, a consequence of pancreatic tissue loss following pancreatectomy, poses a significant challenge for patients undergoing pancreatic surgery. Islet autotransplantation (IAT) offers a promising approach to prevent or alleviate pancreatogenic diabetes, but its application has be...