Comparison of dexmedetomidine with chloral hydrate as sedatives for pediatric patients: A systematic review and meta-analysis

• Published in: Medicine (Baltimore) Vol. 99; no. 31; p. e21008
• Main Authors: Lian, Xianghong, Lin, Yunzhu, Luo, Ting, Yuan, Hongbo, Chen, Yuan
• Format: Journal Article
• Language: English
• Published: United States the Author(s). Published by Wolters Kluwer Health, Inc 31.07.2020; Wolters Kluwer Health
• Subjects: Child; Chloral Hydrate - therapeutic use; Conscious Sedation - methods; Dexmedetomidine - therapeutic use; Humans; Hypnotics and Sedatives - therapeutic use; Systematic Review and Meta-Analysis

Dexmedetomidine (Dex) and chloral hydrate (CH) are the most frequently used sedative agents in pediatric patients. We aimed to systematically review the literature comparing the efficacy and safety of Dex and CH for sedation in pediatric patients. Seven electronic databases and 3 clinical trial regi...