Rifaximin-ciprofloxacin combination therapy is effective in chronic active refractory pouchitis

• Published in: Colorectal disease Vol. 7; no. 2; pp. 182 - 186
• Main Authors: Abdelrazeq, A. S., Kelly, S. M., Lund, J. N., Leveson, S. H.
• Format: Journal Article
• Language: English
• Published: Oxford, UK Blackwell Science Ltd 01.03.2005
• Subjects: Adult; Anti-Infective Agents - therapeutic use; Chronic Disease; ciprofloxacin; Ciprofloxacin - therapeutic use; Drug Therapy, Combination; Female; Humans; Male; Middle Aged; Pouchitis; Pouchitis - drug therapy; Rifamycins - therapeutic use; rifaximin; Statistics, Nonparametric; Treatment Outcome

Objective  Treatment of chronic refractory pouchitis is often difficult and disappointing and some of the affected pouches subsequently fail. This study was conducted to evaluate the efficacy and tolerability of treatment with rifaximin, a nonabsorbable oral antibiotic with immunomdulatory functions...