Update on diabetes mellitus: prevention, treatment, and association with oral diseases

Diabetes mellitus is a prevalent disease that affects millions of people worldwide and has paralleled the growing population of overweight and obese individuals. Early detection of prediabetes and diabetes, as well as lifestyle interventions including diet and exercise, are the overarching objective...

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Published inOral diseases Vol. 14; no. 2; pp. 105 - 114
Main Authors Skamagas, M, Breen, TL, LeRoith, D
Format Journal Article
LanguageEnglish
Published Oxford, UK Blackwell Publishing Ltd 01.03.2008
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Abstract Diabetes mellitus is a prevalent disease that affects millions of people worldwide and has paralleled the growing population of overweight and obese individuals. Early detection of prediabetes and diabetes, as well as lifestyle interventions including diet and exercise, are the overarching objectives in preventing and managing diabetes. For individuals who do not achieve glycemic control with lifestyle modification, there are newer medication classes that assist with weight loss, more physiologic insulins with convenient delivery systems, and old standbys like metformin and thiazolidinediones. Glycemic control along with blood pressure and cholesterol management reduce microvascular and macrovascular disease including cardiovascular events. Mounting evidence demonstrates that diabetes is a risk factor for periodontitis and possibly oral premalignancies and oral cancer. The systemic inflammatory response generated by inflamed periodontal tissue may in turn exacerbate diabetes, worsen cardiovascular outcomes, and increase mortality. Thus, oral medical and surgical physicians are vital in treating oral pathology, recognizing new cases of diabetes, and counseling people with diabetes to promote oral health. This article presents updates in the diagnosis, risk factors, prevention, management, and peri‐oral complications of diabetes to assist oral health professionals in providing optimal care to patients with diabetes.
AbstractList Diabetes mellitus is a prevalent disease that affects millions of people worldwide and has paralleled the growing population of overweight and obese individuals. Early detection of prediabetes and diabetes, as well as lifestyle interventions including diet and exercise, are the overarching objectives in preventing and managing diabetes. For individuals who do not achieve glycemic control with lifestyle modification, there are newer medication classes that assist with weight loss, more physiologic insulins with convenient delivery systems, and old standbys like metformin and thiazolidinediones. Glycemic control along with blood pressure and cholesterol management reduce microvascular and macrovascular disease including cardiovascular events. Mounting evidence demonstrates that diabetes is a risk factor for periodontitis and possibly oral premalignancies and oral cancer. The systemic inflammatory response generated by inflamed periodontal tissue may in turn exacerbate diabetes, worsen cardiovascular outcomes, and increase mortality. Thus, oral medical and surgical physicians are vital in treating oral pathology, recognizing new cases of diabetes, and counseling people with diabetes to promote oral health. This article presents updates in the diagnosis, risk factors, prevention, management, and peri-oral complications of diabetes to assist oral health professionals in providing optimal care to patients with diabetes.
Diabetes mellitus is a prevalent disease that affects millions of people worldwide and has paralleled the growing population of overweight and obese individuals. Early detection of prediabetes and diabetes, as well as lifestyle interventions including diet and exercise, are the overarching objectives in preventing and managing diabetes. For individuals who do not achieve glycemic control with lifestyle modification, there are newer medication classes that assist with weight loss, more physiologic insulins with convenient delivery systems, and old standbys like metformin and thiazolidinediones. Glycemic control along with blood pressure and cholesterol management reduce microvascular and macrovascular disease including cardiovascular events. Mounting evidence demonstrates that diabetes is a risk factor for periodontitis and possibly oral premalignancies and oral cancer. The systemic inflammatory response generated by inflamed periodontal tissue may in turn exacerbate diabetes, worsen cardiovascular outcomes, and increase mortality. Thus, oral medical and surgical physicians are vital in treating oral pathology, recognizing new cases of diabetes, and counseling people with diabetes to promote oral health. This article presents updates in the diagnosis, risk factors, prevention, management, and peri‐oral complications of diabetes to assist oral health professionals in providing optimal care to patients with diabetes.
Author Skamagas, M
LeRoith, D
Breen, TL
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BackLink https://www.ncbi.nlm.nih.gov/pubmed/18302671$$D View this record in MEDLINE/PubMed
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2001; 344
1993; 329
2004; 27
2002; 51
1997; 46
2002; 359
1998; 317
2007; 30
1998; 352
2005; 28
2007; 34
2001; 345
2001; 86
1998; 351
2001a; 29
2007; 298
2002; 87
2006; 29
2002; 346
2007; 2
2000; 321
2001; 18
2006; 368
1996; 67
2003; 361
2005; 352
2002; 30
2005; 353
1997; 20
2004; 141
1997; 68
1999; 67
1999; 22
2000; 71
2003; 290
2004
2006; 1
2001; 28
2003; 74
2003; 31
2001b; 80
2006; 355
2007; 356
2007; 357
1974; 23
1993; 16
2002; 287
2003; 69
2003; 29
1999; 354
2007; 43
1994; 94
1998; 4
2005; 11
2007; 49
Glucose tolerance and mortality: comparison of WHO and American Diabetes Association diagnostic criteria. The DECODE Study Group on behalf of the European Diabetes Epidemiology Group (e_1_2_15_17_1) 1999; 354
e_1_2_15_21_1
e_1_2_15_42_1
e_1_2_15_40_1
Salpeter S (e_1_2_15_41_1) 2006; 1
e_1_2_15_3_1
e_1_2_15_29_1
e_1_2_15_27_1
e_1_2_15_48_1
e_1_2_15_61_1
The DREAM (Diabetes Reduction Assessment with ramipril and rosiglitazone medication) Investigators (e_1_2_15_52_1) 2006; 368
e_1_2_15_25_1
e_1_2_15_23_1
e_1_2_15_44_1
e_1_2_15_9_1
Allen PF (e_1_2_15_4_1) 2003; 69
e_1_2_15_7_1
e_1_2_15_5_1
Tataranni PA (e_1_2_15_49_1) 2004
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e_1_2_15_10_1
e_1_2_15_31_1
e_1_2_15_56_1
e_1_2_15_18_1
e_1_2_15_39_1
e_1_2_15_16_1
e_1_2_15_37_1
e_1_2_15_50_1
e_1_2_15_14_1
e_1_2_15_35_1
e_1_2_15_12_1
e_1_2_15_33_1
e_1_2_15_54_1
e_1_2_15_19_1
e_1_2_15_20_1
e_1_2_15_43_1
e_1_2_15_28_1
e_1_2_15_2_1
e_1_2_15_26_1
e_1_2_15_60_1
e_1_2_15_24_1
e_1_2_15_47_1
e_1_2_15_22_1
e_1_2_15_45_1
e_1_2_15_8_1
e_1_2_15_6_1
e_1_2_15_32_1
e_1_2_15_55_1
e_1_2_15_30_1
e_1_2_15_57_1
e_1_2_15_59_1
e_1_2_15_15_1
e_1_2_15_38_1
e_1_2_15_13_1
e_1_2_15_36_1
e_1_2_15_51_1
Standards of Medical Care in Diabetes (e_1_2_15_46_1) 2007; 30
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Snippet Diabetes mellitus is a prevalent disease that affects millions of people worldwide and has paralleled the growing population of overweight and obese...
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SubjectTerms Blood Glucose - metabolism
cardiovascular disease
Cardiovascular Diseases - complications
Cardiovascular Diseases - metabolism
Dentistry
Diabetes Complications - complications
Diabetes Complications - metabolism
Diabetes Complications - prevention & control
diabetes mellitus
Diabetes Mellitus - classification
Diabetes Mellitus - metabolism
Diabetes Mellitus - prevention & control
Diabetes Mellitus - therapy
Humans
Mouth Diseases - complications
Mouth Diseases - metabolism
Mouth Diseases - prevention & control
periodontitis
Title Update on diabetes mellitus: prevention, treatment, and association with oral diseases
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https://onlinelibrary.wiley.com/doi/abs/10.1111%2Fj.1601-0825.2007.01425.x
https://www.ncbi.nlm.nih.gov/pubmed/18302671
https://search.proquest.com/docview/70336415
Volume 14
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