Rnf32 is not essential for spermatogenesis and male fertility in mice

• Published in: PeerJ (San Francisco, CA) Vol. 13; p. e19794
• Main Authors: Kong, Hao, Yin, Yufeng, Zeng, Ni, Zhu, Yunfei, Cui, Yiqiang
• Format: Journal Article
• Language: English
• Published: United States PeerJ. Ltd 30.07.2025; PeerJ, Inc; PeerJ Inc
• Subjects: Andrology; Animals; Biochemistry; Carbon dioxide; CRISPR; CRISPR-Cas Systems; CRISPR/Cas9; Developmental Biology; Euthanasia; Females; Fertility; Fertility - genetics; Gametocytes; Gene expression; Genetic aspects; Genetic transcription; Histology; Immunofluorescence; Infertility; Male; Males; Mice; Mice, Knockout; Molecular Biology; Morphology; Motility; Ovaries; Phenotypes; Polymerase chain reaction; Postpartum period; Protein interaction; Protein-protein interactions; Proteins; Reverse transcription; Rnf32; Sperm; Sperm Motility - genetics; Spermatids; Spermatocytes; Spermatogenesis; Spermatogenesis - genetics; Testes; Testis; Testis - metabolism; Thermal cycling; Ubiquitin-Protein Ligases - genetics; Ubiquitin-Protein Ligases - metabolism; Testis; Mice; CRISPR/Cas9; Fertility; Spermatogenesis; Rnf32

Ring finger motifs are found in a variety of proteins with diverse functions, often involved in protein-DNA or protein-protein interactions. The -encoded protein contains two such motifs and is predominantly expressed in the testes and ovaries, suggesting that its expression may be regulated by elem...