Multifunctional dietary approach reduces intestinal inflammation in relation with changes in gut microbiota composition in subjects at cardiometabolic risk: the SINFONI project

• Published in: Gut microbes Vol. 17; no. 1; p. 2438823
• Main Authors: Hornero-Ramirez, Hugo, Morissette, Arianne, Marcotte, Bruno, Penhoat, Armelle, Lecomte, Béryle, Panthu, Baptiste, Lessard Lord, Jacob, Thirion, Florence, Van-Den-Berghe, Laurie, Blond, Emilie, Simon, Chantal, Caussy, Cyrielle, Feugier, Nathalie, Doré, Joël, Sanoner, Philippe, Meynier, Alexandra, Desjardins, Yves, Pilon, Geneviève, Marette, André, Cani, Patrice D., Laville, Martine, Vinoy, Sophie, Michalski, Marie-Caroline, Nazare, Julie-Anne
• Format: Journal Article
• Language: English
• Published: United States Taylor & Francis 01.12.2025; Taylor & Francis Group
• Subjects: Adult; Bacteria - classification; Bacteria - genetics; Bacteria - isolation & purification; Bacteria - metabolism; branched chain amino-acids; cardiometabolic risk; Cardiometabolic Risk Factors; Cardiovascular Diseases - prevention & control; Cross-Over Studies; Diet; Dietary Fiber - administration & dosage; Edible Grain; endotoxemia; Endotoxemia - diet therapy; Fatty Acids, Omega-3 - administration & dosage; Feces - chemistry; Feces - microbiology; Female; Gastrointestinal Microbiome; Humans; Inflammation; intestinal inflammation; Intestines - microbiology; Intestines - pathology; Life Sciences; Male; Middle Aged; omega 3; Polyphenols; Polyphenols - administration & dosage; Polyphenols - pharmacology; Polyphenols; cardiometabolic risk; intestinal inflammation; branched chain amino-acids; endotoxemia; omega 3

The development of cardiometabolic (CM) diseases is associated with chronic low-grade inflammation, partly linked to alterations of the gut microbiota (GM) and reduced intestinal integrity. The SINFONI project investigates a multifunctional (MF) nutritional strategy's impact combining different...