Total Lesion Glycolysis Levels as Predictive Indicators in Patients With Metastatic and Recurrent Breast Cancer Undergoing Endocrine Therapy With or Without CDK4/6 Inhibitor

• Published in: Anticancer research Vol. 42; no. 10; pp. 4813 - 4824
• Main Authors: Ozawa, Hiromi, Higuchi, Tomoko, Fujimoto, Yukie, Bun, Ayako, Fukui, Reiko, Kanaoka, Haruka, Nagahashi, Masayuki, Kitajima, Kazuhiro, Yamakado, Koichiro, Miyoshi, Yasuo
• Format: Journal Article
• Language: English
• Published: Athens International Institute of Anticancer Research 01.10.2022
• Subjects: Breast cancer; Confidence intervals; Cyclin-dependent kinase 4; Endocrine therapy; ErbB-2 protein; Estrogen receptors; Estrogens; Glycolysis; Lesions; Mathematical analysis; Metabolism; Metastases; Metastasis; Parameter identification; Parameter sensitivity; Patients; Positron emission; Positron emission tomography; Sensitivity; Tumors

Background/Aim: Endocrine therapy (ET) with or without CDK4/6 inhibitors is the primary treatment choice for patients with estrogen receptor (ER)-positive and HER2-negative subtype of metastatic breast cancer (MBC). We examined the metabolic parameters identified using 18F-fluorodeoxyglucose-positro...