GDNF signaling implemented by GM1 ganglioside; failure in Parkinson's disease and GM1-deficient murine model - Hadaczek, Piotr; Wu, Gusheng; Sharma, Nitasha; Ciesielska, Agnieszka; Bankiewicz, Krystof; Davidow, Amy L.; Lu, Zi-Hua; Forsayeth, John; Ledeen, Robert W. (Experimental neurology, 2015)
Keywords: Animals; B4galnt1; Cell Line; Disease Models, Animal; G(M1) Ganglioside - analogs & derivatives; G(M1) Ganglioside - metabolism; Gangliosides - metabolism; GDNF; Gene Knockdown Techniques; Glial Cell Line-Derived Neurotrophic Factor - metabolism; GM1 analogs; GM1 ganglioside; Humans; Immunoblotting; Immunohistochemistry; LIGA20; Mice; Neuroprotection; Parkinson Disease - metabolism; Parkinson's disease; RET signaling; Signal Transduction - physiology; Sphingosine - analogs & derivatives; Sphingosine - metabolism; Neuroprotection; BSS; LIGA20; Parkinson's disease; KO; BDNF; SNpc; aSyn; HT; NGF; GM1 ganglioside; GM1 analogs; GDNF; PD; TH; B4galnt1; PBST; RET signaling; CtxB; DA; WT; HPTLC