Production of rosmarinic acid and lithospermic acid B in Ti transformed Salvia miltiorrhiza cell suspension cultures

• Published in: Process biochemistry (1991) Vol. 34; no. 8; pp. 777 - 784
• Main Authors: Chen, Hui, Chen, Feng, Zhang, Yin-Lin, Song, Jing-Yuan
• Format: Journal Article
• Language: English
• Published: Elsevier Ltd 01.10.1999
• Subjects: Bioreactor; Conductivity; Initial pH; Lithosperrnic acid B; Rosmarinic acid; Salvia miltiorrhiza; Ti transformed cell culture; Salvia miltiorrhiza; Bioreactor; Ti transformed cell culture; Conductivity; Initial pH; Rosmarinic acid; Lithosperrnic acid B

A Ti transformed cell culture of S. miltiorrhiza demonstrated the ability to produce rosmarinic acid (RA) and lithospermic acid B (LAB) as determined by HPLC. A time course of biomass accumulation, phenolic compound formation, medium pH and conductivity as well as sugar, nitrate, ammonium and phosph...