Knock-down of circular RNA H19 induces human adipose-derived stem cells adipogenic differentiation via a mechanism involving the polypyrimidine tract-binding protein 1

• Published in: Experimental cell research Vol. 387; no. 2; p. 111753
• Main Authors: Zhu, Yiyi, Gui, Weiwei, Lin, Xihua, Li, Hong
• Format: Journal Article
• Language: English
• Published: United States Elsevier Inc 15.02.2020
• Subjects: Adipogenic differentiation; Circular RNA; Human adipose-derived stem cells; Metabolic syndrome; Polypyrimidine tract-binding protein 1; Sterol-regulatory element binding proteins; Adipogenic differentiation; Polypyrimidine tract-binding protein 1; Sterol-regulatory element binding proteins; Human adipose-derived stem cells; Circular RNA; Metabolic syndrome

The metabolic syndrome (MetS) is characterized of a cluster of medical disorders. Altered function of adipose tissue has a significant impact on whole-body metabolism and represents a key driver for MetS. In this study, we aim to explore the function of human circular RNA H19 (hsa_circH19) in human...