Frailty is associated with elevated CRP trajectories and higher numbers of neutrophils and monocytes

• Published in: Experimental gerontology Vol. 125; p. 110674
• Main Authors: Samson, Leonard Daniël, Boots, A. Mieke H., Verschuren, W.M. Monique, Picavet, H. Susan J., Engelfriet, Peter, Buisman, Anne-Marie
• Format: Journal Article
• Language: English
• Published: England Elsevier Inc 01.10.2019

With aging, the human immune system undergoes several changes. The clinical relevance of these changes, however, is relatively unknown. We investigated immunological aspects of human aging in relation to frailty in the Doetinchem Cohort Study (DCS). We calculated a frailty index score based on 36 he...