The impact of a Facebook campaign among mothers on HPV vaccine uptake among their daughters: A randomized field study

• Published in: Gynecologic oncology Vol. 160; no. 1; pp. 106 - 111
• Main Authors: Chodick, Gabriel, Teper, Gally Rosenfeld, Levi, Shai, Kopel, Hagit, Kleinbort, Asaf, Khen, Eviatar, Schejter, Eduardo, Shalev, Varda, Stein, Michal, Lewis, Nehama
• Format: Journal Article
• Language: English
• Published: United States Elsevier Inc 01.01.2021
• Subjects: childhood immunization; HPV vaccine; social campaign; HPV vaccine; childhood immunization; social campaign
• DOI: 10.1016/j.ygyno.2020.10.037
• ISSN: 0090-8258

The popularity of social networks provide an incredible opportunity to enhance the impact of preventive medicine programs. We aimed to assess whether a targeted Facebook campaign among mothers may increase the uptake of human Papilloma virus (HPV) immunization among their 8th-grade daughters. This field study was conducted among the members of a state-mandated health organization in Israel. Included were all 21,592 members who were mothers to 14 year-old daughters in the 2018-19 school-year. A total of 17,271 (80%) were randomly allocated to the campaign arm and the rest (n=4,321) were selected as a reference group. The Facebook ads addressed issues and concerns regarding HPV-related diseases and HPV vaccine. Main outcome measures were Facebook metrics on exposure to campaign and HPV immunization among eighth grade daughters of the study participants. Between 8/2018-10/2018, Facebook ads were shown 1.8-million times (a reach of 88%). The uptake of HPV vaccine among daughters of women allocated to the campaign arm (55.3%) was similar (p = 0.749) to 55.0% in the control group. The only significant differences between study groups were observed when stratifying by SES level. In the lowest SES quartile, Facebook campaign significantly (p = .02) reduced vaccine uptake (35% vs. 39.0%), with a relative risk of 0.90 (95%CI: 0.82-0.98), while in the second SES quartile, Facebook campaign increased vaccine uptake from 52.6% to 55.8%, with a RR of 1.06 (95%CI,1.00-1.12). Among mothers in higher SES levels, daughters of exposed and unexposed mothers had similar immunization rates. Facebook campaign may increase the uptake of HPV vaccine among daughters to mothers of medium-to-low SES level, but it may reduce vaccination among lower SES groups. •A large randomized controlled study on the effectiveness of Facebook campaigns on the uptake of HPV immunizations.•The campaign aimed a potential target population of 17,271 mothers to 14 year-old daughters.•In families of low SES, our campaign reduced uptake by 10% while in low-medium level, it increased the uptake by 6%.•HPV promotion campaign in social media might be a double-edged sword depending on target population.