Absence of an effect of high nitrate intake from beetroot juice on blood pressure in treated hypertensive individuals: a randomized controlled trial

• Published in: The American journal of clinical nutrition Vol. 102; no. 2; pp. 368 - 375
• Main Authors: Bondonno, Catherine P, Liu, Alex H, Croft, Kevin D, Ward, Natalie C, Shinde, Sujata, Moodley, Yuben, Lundberg, Jon O, Puddey, Ian B, Woodman, Richard J, Hodgson, Jonathan M
• Format: Journal Article
• Language: English
• Published: United States American Society for Clinical Nutrition, Inc 01.08.2015
• Subjects: Aged; Antihypertensive Agents - therapeutic use; Beta vulgaris - chemistry; Beverages - analysis; Blood pressure; Cardiovascular disease; Combined Modality Therapy; Cross-Over Studies; Diet; Double-Blind Method; Drug Resistance; Drug Resistance, Multiple; Drug Therapy, Combination; Effects; Female; Fruit juices; Humans; Hypertension - diet therapy; Hypertension - drug therapy; Male; Middle Aged; Nitrates - analysis; Nitrates - therapeutic use; Nitrates - urine; Nitrites - analysis; Nitrites - blood; Nitrites - urine; Plant Roots - chemistry; Saliva - chemistry; Vegetables; Western Australia; Western Australia; blood pressure; nitric oxide; nitrate; hypertension; beetroot

Dietary nitrate, which is in green leafy vegetables and beetroot, decreases blood pressure through the enterosalivary nitrate-nitrite-nitric oxide pathway in healthy individuals. Whether similar effects would occur in individuals with treated hypertension and, therefore, at increased risk of cardiov...