Adaptation of the human population to the environment: Current knowledge, clues from Czech cytogenetic and “omics” biomonitoring studies and possible mechanisms
The human population is continually exposed to numerous harmful environmental stressors, causing negative health effects and/or deregulation of biomarker levels. However, studies reporting no or even positive impacts of some stressors on humans are also sometimes published. The main aim of this revi...
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| Published in | Mutation research Vol. 773; pp. 188 - 203 |
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| Main Authors | , , , , , , |
| Format | Journal Article |
| Language | English |
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Netherlands
Elsevier B.V
01.07.2017
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| Abstract | The human population is continually exposed to numerous harmful environmental stressors, causing negative health effects and/or deregulation of biomarker levels. However, studies reporting no or even positive impacts of some stressors on humans are also sometimes published. The main aim of this review is to provide a comprehensive overview of the last decade of Czech biomonitoring research, concerning the effect of various levels of air pollution (benzo[a]pyrene) and radiation (uranium, X-ray examination and natural radon background), on the differently exposed population groups. Because some results obtained from cytogenetic studies were opposite than hypothesized, we have searched for a meaningful interpretation in genomic/epigenetic studies.
A detailed analysis of our data supported by the studies of others and current epigenetic knowledge, leads to a hypothesis of the versatile mechanism of adaptation to environmental stressors via DNA methylation settings which may even originate in prenatal development, and help to reduce the resulting DNA damage levels. This hypothesis is fully in agreement with unexpected data from our studies (e.g. lower levels of DNA damage in subjects from highly polluted regions than in controls or in subjects exposed repeatedly to a pollutant than in those without previous exposure), and is also supported by differences in DNA methylation patterns in groups from regions with various levels of pollution.
In light of the adaptation hypothesis, the following points may be suggested for future research: (i) the chronic and acute exposure of study subjects should be distinguished; (ii) the exposure history should be mapped including place of residence during the life and prenatal development; (iii) changes of epigenetic markers should be monitored over time.
In summary, investigation of human adaptation to the environment, one of the most important processes of survival, is a new challenge for future research in the field of human biomonitoring that may change our view on the results of biomarker analyses and potential negative health impacts of the environment. |
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| AbstractList | The human population is continually exposed to numerous harmful environmental stressors, causing negative health effects and/or deregulation of biomarker levels. However, studies reporting no or even positive impacts of some stressors on humans are also sometimes published. The main aim of this review is to provide a comprehensive overview of the last decade of Czech biomonitoring research, concerning the effect of various levels of air pollution (benzo[a]pyrene) and radiation (uranium, X-ray examination and natural radon background), on the differently exposed population groups. Because some results obtained from cytogenetic studies were opposite than hypothesized, we have searched for a meaningful interpretation in genomic/epigenetic studies. A detailed analysis of our data supported by the studies of others and current epigenetic knowledge, leads to a hypothesis of the versatile mechanism of adaptation to environmental stressors via DNA methylation settings which may even originate in prenatal development, and help to reduce the resulting DNA damage levels. This hypothesis is fully in agreement with unexpected data from our studies (e.g. lower levels of DNA damage in subjects from highly polluted regions than in controls or in subjects exposed repeatedly to a pollutant than in those without previous exposure), and is also supported by differences in DNA methylation patterns in groups from regions with various levels of pollution. In light of the adaptation hypothesis, the following points may be suggested for future research: (i) the chronic and acute exposure of study subjects should be distinguished; (ii) the exposure history should be mapped including place of residence during the life and prenatal development; (iii) changes of epigenetic markers should be monitored over time. In summary, investigation of human adaptation to the environment, one of the most important processes of survival, is a new challenge for future research in the field of human biomonitoring that may change our view on the results of biomarker analyses and potential negative health impacts of the environment. The human population is continually exposed to numerous harmful environmental stressors, causing negative health effects and/or deregulation of biomarker levels. However, studies reporting no or even positive impacts of some stressors on humans are also sometimes published. The main aim of this review is to provide a comprehensive overview of the last decade of Czech biomonitoring research, concerning the effect of various levels of air pollution (benzo[a]pyrene) and radiation (uranium, X-ray examination and natural radon background), on the differently exposed population groups. Because some results obtained from cytogenetic studies were opposite than hypothesized, we have searched for a meaningful interpretation in genomic/epigenetic studies. A detailed analysis of our data supported by the studies of others and current epigenetic knowledge, leads to a hypothesis of the versatile mechanism of adaptation to environmental stressors via DNA methylation settings which may even originate in prenatal development, and help to reduce the resulting DNA damage levels. This hypothesis is fully in agreement with unexpected data from our studies (e.g. lower levels of DNA damage in subjects from highly polluted regions than in controls or in subjects exposed repeatedly to a pollutant than in those without previous exposure), and is also supported by differences in DNA methylation patterns in groups from regions with various levels of pollution. In light of the adaptation hypothesis, the following points may be suggested for future research: (i) the chronic and acute exposure of study subjects should be distinguished; (ii) the exposure history should be mapped including place of residence during the life and prenatal development; (iii) changes of epigenetic markers should be monitored over time. In summary, investigation of human adaptation to the environment, one of the most important processes of survival, is a new challenge for future research in the field of human biomonitoring that may change our view on the results of biomarker analyses and potential negative health impacts of the environment.The human population is continually exposed to numerous harmful environmental stressors, causing negative health effects and/or deregulation of biomarker levels. However, studies reporting no or even positive impacts of some stressors on humans are also sometimes published. The main aim of this review is to provide a comprehensive overview of the last decade of Czech biomonitoring research, concerning the effect of various levels of air pollution (benzo[a]pyrene) and radiation (uranium, X-ray examination and natural radon background), on the differently exposed population groups. Because some results obtained from cytogenetic studies were opposite than hypothesized, we have searched for a meaningful interpretation in genomic/epigenetic studies. A detailed analysis of our data supported by the studies of others and current epigenetic knowledge, leads to a hypothesis of the versatile mechanism of adaptation to environmental stressors via DNA methylation settings which may even originate in prenatal development, and help to reduce the resulting DNA damage levels. This hypothesis is fully in agreement with unexpected data from our studies (e.g. lower levels of DNA damage in subjects from highly polluted regions than in controls or in subjects exposed repeatedly to a pollutant than in those without previous exposure), and is also supported by differences in DNA methylation patterns in groups from regions with various levels of pollution. In light of the adaptation hypothesis, the following points may be suggested for future research: (i) the chronic and acute exposure of study subjects should be distinguished; (ii) the exposure history should be mapped including place of residence during the life and prenatal development; (iii) changes of epigenetic markers should be monitored over time. In summary, investigation of human adaptation to the environment, one of the most important processes of survival, is a new challenge for future research in the field of human biomonitoring that may change our view on the results of biomarker analyses and potential negative health impacts of the environment. The human population is continually exposed to numerous harmful environmental stressors, causing negative health effects and/or deregulation of biomarker levels. However, studies reporting no or even positive impacts of some stressors on humans are also sometimes published. The main aim of this review is to provide a comprehensive overview of the last decade of Czech biomonitoring research, concerning the effect of various levels of air pollution (benzo[a]pyrene) and radiation (uranium, X-ray examination and natural radon background), on the differently exposed population groups. Because some results obtained from cytogenetic studies were opposite than hypothesized, we have searched for a meaningful interpretation in genomic/epigenetic studies. A detailed analysis of our data supported by the studies of others and current epigenetic knowledge, leads to a hypothesis of the versatile mechanism of adaptation to environmental stressors via DNA methylation settings which may even originate in prenatal development, and help to reduce the resulting DNA damage levels. This hypothesis is fully in agreement with unexpected data from our studies (e.g. lower levels of DNA damage in subjects from highly polluted regions than in controls or in subjects exposed repeatedly to a pollutant than in those without previous exposure), and is also supported by differences in DNA methylation patterns in groups from regions with various levels of pollution. In light of the adaptation hypothesis, the following points may be suggested for future research: (i) the chronic and acute exposure of study subjects should be distinguished; (ii) the exposure history should be mapped including place of residence during the life and prenatal development; (iii) changes of epigenetic markers should be monitored over time. In summary, investigation of human adaptation to the environment, one of the most important processes of survival, is a new challenge for future research in the field of human biomonitoring that may change our view on the results of biomarker analyses and potential negative health impacts of the environment. |
| Author | Rossner, Pavel Svecova, Vlasta Sram, Radim J. Pokorna, Michaela Topinka, Jan Zölzer, Friedo Rossnerova, Andrea |
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| BackLink | https://www.ncbi.nlm.nih.gov/pubmed/28927528$$D View this record in MEDLINE/PubMed |
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| Cites_doi | 10.1002/em.2850110210 10.1186/gb-2010-11-3-110 10.1289/ehp.6310 10.1155/2013/416701 10.1016/j.tree.2016.01.005 10.1016/j.mrfmmm.2013.02.003 10.1289/ehp.1307892 10.1016/j.mrrev.2016.05.003 10.1289/ehp.1408459 10.1093/mutage/13.5.475 10.1016/j.ijheh.2014.01.001 10.1002/path.1024 10.1093/carcin/9.1.81 10.1146/annurev.bi.57.070188.001025 10.1093/mutage/gev032 10.2203/dose-response.08-016.Scott 10.1093/molbev/msv046 10.1080/1354750X.2016.1276627 10.1155/2015/123484 10.1158/1055-9965.EPI-05-0456 10.1093/mutage/geq057 10.1111/j.1432-1033.1977.tb11869.x 10.1897/IEAM_2008-080.1 10.1371/journal.pone.0107653 10.1007/s00038-012-0369-6 10.1038/nbt.2890 10.1183/16000617.0034-2016 10.1093/mutage/ges057 10.1016/0921-8777(92)90089-L 10.2203/dose-response.07-024.Rithidech 10.2217/epi.15.114 10.1038/emm.2017.10 10.1113/jphysiol.2014.271460 10.1016/0165-1161(85)90015-9 10.1093/nar/18.2.331 10.1016/S1383-5742(02)00025-X 10.1038/nmeth.3152 10.1016/0165-1161(88)90013-1 10.1007/s00411-012-0422-0 10.1016/j.mrfmmm.2010.12.008 10.1016/j.mrfmmm.2011.06.001 10.1590/S1415-47572008000300002 10.1080/10807030009380063 10.1016/j.envres.2016.08.026 10.1096/fj.201601059RR 10.1101/gr.152231.112 10.1097/00004032-198303000-00001 10.1126/science.1197296 10.1016/S0165-1218(96)00060-2 10.1007/s00420-012-0795-z 10.1073/pnas.0806560105 10.1016/j.mrfmmm.2015.08.001 10.1289/ehp.1205925 10.1093/eurpub/cku102 10.2967/jnmt.115.166074 10.3892/ijmm.2014.1994 10.1016/j.arr.2007.08.007 10.1007/s10517-016-3336-z 10.1101/gad.947102 10.1085/jgp.23.5.585 10.1093/mutage/ges058 10.1016/j.mrfmmm.2011.01.004 10.1159/000441889 10.1289/ehp.99107475 10.4161/15592294.2014.989741 10.1093/mutage/get026 10.1016/j.envint.2015.12.009 10.1016/j.mrfmmm.2009.04.008 10.1016/j.ijheh.2013.01.008 10.1038/nature13544 10.1096/fj.12-220350 10.1016/j.mrfmmm.2016.10.004 10.1097/GCO.0000000000000252 10.1128/JB.175.18.6010-6017.1993 10.1667/RR14023.1 10.1016/j.dnarep.2011.03.007 10.2217/epi.15.60 10.1080/15287399309531800 10.1159/000022024 10.1093/hmg/ddu751 10.1128/JB.173.12.3656-3662.1991 10.1159/000338084 10.1016/0926-6917(95)90066-7 10.1098/rstb.2011.0330 10.1093/toxsci/kfu210 10.1016/j.mrfmmm.2005.07.009 10.1016/S2352-3026(15)00094-0 10.1038/nrg2732 10.1093/ije/dyv043 |
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| Keywords | PAR PCBs MTase c-PAHs WGBS AS3MT FG/100 FITC DNA methylation AHR2 KEGG PBL Cy-3 MN Environmental exposure CEN+MN CEN-MN Adaptive response DAPI 5mC BER PCA XRCC SNP BNC Micronuclei B[a]P FISH NHEJ CBMN assay MNNG |
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| References | Zölzer, Havrankova, Freitinger Skalicka, Rossnerova, Sram (bib0265) 2015; 147 Leuraud, Richardson, Cardis, Daniels, Gillies, ÓHagan, Hamra, Haylock, Laurier, Moissonnier, Schubauer-Berigan, Thierry-Chef, Kesminiene (bib0150) 2015; 2 Gautier, Bunemann, Grotjahn (bib0485) 1977; 80 Rossner, Uhlirova, Beskid, Rossnerova, Svecova, Sram (bib0215) 2011; 713 Guidelines (bib0245) 2010 Brozmanova, Kleibl, Vlckova, Skorvaga, Cermakova, Margison (bib0050) 1990; 18 Jelinek, Kleibl, Dexter, Margison (bib0060) 1988; 9 Barnthouse, Glaser, DeSantis (bib0065) 2009; 5 Toprani, Das (bib0130) 2015; 30 Fenech, Morley (bib0475) 1985; 147 Seisenberger, Peat, Hore, Santos, Dean, Reik (bib0410) 2013; 368 Guo, Zhu, Yan, Li, Hu, Lian, Yan, Ren, Lin, Li, Jin, Shi, Liu, Wang, Wang, Wei, Li, Guo, Wu, Fan, Yong, Wen, Xie, Tang, Qiao (bib0395) 2014; 511 Rossner, Tulupova, Rossnerova, Libalova, Honkova, Gmuender, Uhlirova, Pastorkova, Svecova, Topinka, Sram (bib0220) 2015; 780 Dimova, Bryant, Chankova (bib0015) 2008; 31 Scott, Belinsky, Leng, Lin, Wilder, Damiani (bib0175) 2009; 7 Kanherkar, Bhatia-Dey, Csoka (bib0385) 2014; 49 Fenech, Kirsch-Volders, Rossnerova, Sram, Romm, Bolognesi, Ramakumar, Soussaline, Schunck, Elhajouji, Anwar, Bonassi (bib0480) 2013; 216 Wirgin, Roy, Loftus, Chambers, Franks, Hahn (bib0070) 2011; 331 Henning, Rudd, Hoar (bib0285) 1988; 203 Mattson (bib0095) 2008; 7 WHO (bib0280) 2009 Kubota, Miyake, Hirasawa (bib0415) 2013 Ziller, Hansen, Meissnet, Aryee (bib0510) 2015; 12 Doudoroff (bib0010) 1940; 23 Jeck, Sharpless (bib0520) 2014; 32 Guida, Sandanger, Castagné, Campanella, Polidoro, Palli, Krogh, Tumino, Sacerdote, Panico, Severi, Kyrtopoulos, Georgiadis, Vermeulen, Lund, Vineis, Chadeau-Hyam (bib0425) 2015; 24 Rojas, Rager, Smeester, Bailey, Drobna, Rubio-Andrade, Styblo, Garcia-Vargas, Fry (bib0365) 2015; 143 Izzotti, Larghero, Longobardi, Cartiglia, Camoirano, Steele, De Flora (bib0085) 2011; 717 Committee on the Epidemiology of Air Pollutants (bib0305) 1985 Ko, Butcher, Leong (bib0320) 2014; WJG 20 Laufer, Kapalanga, Castellani, Diehl, Yan, Singh (bib0370) 2015; 7 Bae, Kim, Cha, Choi, Shin, An, Lee, Lee, Kim, Nam, An (bib0170) 2015; 35 Moore, Titenko-Holland, Quintana, Smith (bib0290) 1993; 40 Rossnerova, Tulupova, Tabashidze, Schmuczerova, Dostal, Rossner, Gmuender, Sram (bib0225) 2013; 741-742 Wojcik, Shadley (bib0160) 2000; 6 Sram, Dostal, Libalova, Rossner, Rossnerova, Svecova, Topinka, Bartonova (bib0535) 2013 Stevens, Cheng, Li, Xie, Hong, Maire, Ligon, Hirst, Marra, Costello, Wang (bib0390) 2013; 23 IARC (bib0235) 2012 Rossnerova, Spatova, Rossner, Novakova, Solansky, Sram (bib0540) 2011; 708 Morohoshi, Hayashi, Munkata (bib0030) 1993; 175 Davis, Yu, Preston, Epifanova, Degteva, Akleyev (bib0155) 2015; 184 Volkert (bib0020) 1988; 11 Henschel, Atkinson, Zeka, Tertle, Analitis, Katsouyanni, Chanel, Pascal, Forsberg, Medina, Goodman (bib0330) 2012; 57 Zaichkina, Dyukina, Rozanova, Simonova, Romanchenko, Sorokina, Zakrzhevskaya, Yusupov, Bagratashvili (bib0110) 2016; 161 Andersen, Sram, Scasny, Gurzau, Fucic, Gribaldo, Rossner, Rossnerova, Kohlova, Maca, Zverinova, Gajdosova, Moshammer, Rudnai, Knudsen (bib0500) 2016; 88 Kleibl (bib0045) 2002; 512 Brody, Rudel (bib0315) 2003; 111 Pacchierotti, Spanò (bib0080) 2015 Beskid, Dusek, Solansky, Sram (bib0240) 2006; 594 Hui, Chiu (bib0505) 2016; 28 Sokolov, Neumann (bib0165) 2016; 17 Caratero, Courtade, Bonnet, Planel, Caratero (bib0115) 1998; 44 Laird (bib0490) 2010; 11 Tobi, Slieker, Stein, Suchiman, Slagboom, van Zwet, Heijmans, Lumey (bib0445) 2015; 44 Speit (bib0465) 2013; 28 Dulout, Grillo, Seoane, Maderna, Nilsson, Vahter, Darroudi, Natarajan (bib0340) 1996; 370 Chen, Luan, Shieh, Chen, Kung, Soong, Yeh, Chou, Mong, Wu, Sun, Deng, Wu, Shen (bib0135) 2007; 25 Rossnerova, Spatova, Rossner, Solansky, Sram (bib0190) 2009; 5-6 Nersesyan, Fenech, Bolognesi, Misik, Setayesh, Wultsch, Bonassi, Thomas (bib0455) 2016; 770 McMichael, Giles (bib0310) 1988; 48 Wild (bib0525) 2005; 14 Rossner, Svecova, Schmuczerova, Milcova, Tabashidze, Topinka, Pastorkova, Sram (bib0195) 2013; 28 Reid, Cornfield, Markush, Siegel, Peuderson, Heintzel (bib0300) 1966; 19 Zölzer, Hon, Skalicka, Havrankova, Navratil, Rosina, Skopek (bib0260) 2013; 86 Siroux, Agier, Slama (bib0530) 2016; 25 Markunas, Xu, Harlid, Wade, Lie, Taylor, Wilcox (bib0355) 2014; 122 Rossner, Rossnerova, Spatova, Beskid, Uhlirova, Libalova, Solansky, Topinka, Sram (bib0200) 2013; 28 Heijmans, Tobi, Stein, Putter, Blauw, Susser, Slagboom, Lumey (bib0375) 2008; 105 Cao-Lei, Massart, Suderman, Machnes, Elgbeili, Laplante, Szyf, King (bib0380) 2014; 9 Bernal, Dolinoy, Huang, Skaar, Weinhouse, Jirtle (bib0180) 2013; 27 Sanz, Kota, Feil (bib0400) 2010; 11 Rithidech, Scott (bib0125) 2008; 6 Gourabi, Mozdarani (bib0350) 1998; 13 Vaughan, Sedgwick (bib0040) 1991; 173 Izzotti, Pulliero (bib0090) 2014; 217 Bateson, Gluckman, Hanson (bib0450) 2014; 592 Baldwin, Grantham (bib0100) 2015; 43 Vrijens, Bollati, Nawrot (bib0515) 2015; 123 Rossnerova, Spatova, Schunck, Sram (bib0205) 2011; 26 Angelis, Briza, Satava, Skakal, Veleminsky, Vlasak, Kleibl, Margison (bib0055) 1992; 273 Hillman, Finer, Smart, Mathews, Lowe, Rakyan, Hitman, Williams (bib0440) 2015; 10 Yang, Aamodt, Dalhus, Balasingham, Helle, Andersen, Tønjum, Alseth, Rognes, Bjørås (bib0035) 2011; 10 Schlebusch, Gattepaille, Engström, Vahter, Jakobsson, Broberg (bib0075) 2015; 32 Moran, Arribas, Esteller (bib0495) 2016; 8 Lindahl, Sedgwick (bib0025) 1988; 57 Esteller, Herman (bib0295) 2002; 196 Natarajan, Boei, Darroudi, Van Diemen, Dulout, Hande, Ramalho (bib0335) 1996; 104 Dejmek, Selevan, Benes, Solansky, Sram (bib0435) 1999; 107 Rossnerova, Spatova, Rossner, Solansky, Sram (bib0185) 2009; 669 Sram (bib0210) 2010; 5–6 Øller, Mousseau (bib0140) 2016; 31 Koestler, Avissar-Whiting, Houseman, Karagas, Marsit (bib0360) 2013; 121 Hickey, Bowers, Clelland (bib0105) 1983; 44 Zölzer, Hon, Skalicka, Havrankova, Navratil, Rosina, Skopek (bib0250) 2012; 136 Rossnerova, Honkova, Pavlikova, Freitinger Skalicka, Havrankova, Solansky, Rossner, Sram, Zölzer (bib0270) 2016; 793 Vahter, Concha, Nermell, Nilsson, Dulout, Natarajan (bib0345) 1995; 293 Hemminki, Fosti, Khyatti, Anwar, Mousavi (bib0325) 2014; 24 Zölzer, Krizova, Freitinger-Skalicka, Rossnerova, Sram (bib0275) 2017; 3 Sram, Svecova, Rossnerova (bib0460) 2016; 770 Zölzer, Hon, Skalicka, Havrankova, Navratil, Rosina, Skopek (bib0255) 2012; 51 Gourabi, Mozdarani (bib0120) 1998; 13 Vineis, Chatziioannou, Cunliffe, Flanagan, Hanson, Kirsch-Volders, Kyrtopoulos (bib0420) 2017; 31 Shi, Mothersill, Seymour (bib0145) 2016; 151 Evans, Neary, Williamson (bib0470) 1959; 1 Kim, Costello (bib0430) 2017; 49 Dobzhansky (bib0005) 1968 Bird (bib0405) 2002; 16 Rossnerova, Tulupova, Spatova, Pokorna, Svecova, Topinka, Gmuender, Sram, Rossner (bib0230) 2016 Beskid (10.1016/j.mrrev.2017.07.002_bib0240) 2006; 594 Tobi (10.1016/j.mrrev.2017.07.002_bib0445) 2015; 44 Mattson (10.1016/j.mrrev.2017.07.002_bib0095) 2008; 7 Baldwin (10.1016/j.mrrev.2017.07.002_bib0100) 2015; 43 Caratero (10.1016/j.mrrev.2017.07.002_bib0115) 1998; 44 Rossnerova (10.1016/j.mrrev.2017.07.002_bib0205) 2011; 26 Andersen (10.1016/j.mrrev.2017.07.002_bib0500) 2016; 88 Ziller (10.1016/j.mrrev.2017.07.002_bib0510) 2015; 12 Rithidech (10.1016/j.mrrev.2017.07.002_bib0125) 2008; 6 Volkert (10.1016/j.mrrev.2017.07.002_bib0020) 1988; 11 Hickey (10.1016/j.mrrev.2017.07.002_bib0105) 1983; 44 Rossner (10.1016/j.mrrev.2017.07.002_bib0200) 2013; 28 Izzotti (10.1016/j.mrrev.2017.07.002_bib0090) 2014; 217 Dejmek (10.1016/j.mrrev.2017.07.002_bib0435) 1999; 107 Dulout (10.1016/j.mrrev.2017.07.002_bib0340) 1996; 370 Moore (10.1016/j.mrrev.2017.07.002_bib0290) 1993; 40 Laufer (10.1016/j.mrrev.2017.07.002_bib0370) 2015; 7 Chen (10.1016/j.mrrev.2017.07.002_bib0135) 2007; 25 Leuraud (10.1016/j.mrrev.2017.07.002_bib0150) 2015; 2 Toprani (10.1016/j.mrrev.2017.07.002_bib0130) 2015; 30 Heijmans (10.1016/j.mrrev.2017.07.002_bib0375) 2008; 105 Sram (10.1016/j.mrrev.2017.07.002_bib0210) 2010; 5–6 Rojas (10.1016/j.mrrev.2017.07.002_bib0365) 2015; 143 IARC (10.1016/j.mrrev.2017.07.002_bib0235) 2012 Wirgin (10.1016/j.mrrev.2017.07.002_bib0070) 2011; 331 Zölzer (10.1016/j.mrrev.2017.07.002_bib0275) 2017; 3 Vaughan (10.1016/j.mrrev.2017.07.002_bib0040) 1991; 173 Gourabi (10.1016/j.mrrev.2017.07.002_bib0350) 1998; 13 Vineis (10.1016/j.mrrev.2017.07.002_bib0420) 2017; 31 Barnthouse (10.1016/j.mrrev.2017.07.002_bib0065) 2009; 5 Hui (10.1016/j.mrrev.2017.07.002_bib0505) 2016; 28 Koestler (10.1016/j.mrrev.2017.07.002_bib0360) 2013; 121 Brody (10.1016/j.mrrev.2017.07.002_bib0315) 2003; 111 Scott (10.1016/j.mrrev.2017.07.002_bib0175) 2009; 7 Jeck (10.1016/j.mrrev.2017.07.002_bib0520) 2014; 32 Zölzer (10.1016/j.mrrev.2017.07.002_bib0250) 2012; 136 Zölzer (10.1016/j.mrrev.2017.07.002_bib0260) 2013; 86 Reid (10.1016/j.mrrev.2017.07.002_bib0300) 1966; 19 Cao-Lei (10.1016/j.mrrev.2017.07.002_bib0380) 2014; 9 Rossner (10.1016/j.mrrev.2017.07.002_bib0215) 2011; 713 Angelis (10.1016/j.mrrev.2017.07.002_bib0055) 1992; 273 Yang (10.1016/j.mrrev.2017.07.002_bib0035) 2011; 10 WHO (10.1016/j.mrrev.2017.07.002_bib0280) 2009 Fenech (10.1016/j.mrrev.2017.07.002_bib0480) 2013; 216 Guida (10.1016/j.mrrev.2017.07.002_bib0425) 2015; 24 Izzotti (10.1016/j.mrrev.2017.07.002_bib0085) 2011; 717 Kim (10.1016/j.mrrev.2017.07.002_bib0430) 2017; 49 Sram (10.1016/j.mrrev.2017.07.002_bib0535) 2013 Rossnerova (10.1016/j.mrrev.2017.07.002_bib0230) 2016 Rossnerova (10.1016/j.mrrev.2017.07.002_bib0270) 2016; 793 Vahter (10.1016/j.mrrev.2017.07.002_bib0345) 1995; 293 Gautier (10.1016/j.mrrev.2017.07.002_bib0485) 1977; 80 Rossner (10.1016/j.mrrev.2017.07.002_bib0195) 2013; 28 Kubota (10.1016/j.mrrev.2017.07.002_bib0415) 2013 Kanherkar (10.1016/j.mrrev.2017.07.002_bib0385) 2014; 49 Rossner (10.1016/j.mrrev.2017.07.002_bib0220) 2015; 780 Rossnerova (10.1016/j.mrrev.2017.07.002_bib0225) 2013; 741-742 Schlebusch (10.1016/j.mrrev.2017.07.002_bib0075) 2015; 32 Henning (10.1016/j.mrrev.2017.07.002_bib0285) 1988; 203 Wild (10.1016/j.mrrev.2017.07.002_bib0525) 2005; 14 Kleibl (10.1016/j.mrrev.2017.07.002_bib0045) 2002; 512 Laird (10.1016/j.mrrev.2017.07.002_bib0490) 2010; 11 Rossnerova (10.1016/j.mrrev.2017.07.002_bib0185) 2009; 669 Zölzer (10.1016/j.mrrev.2017.07.002_bib0255) 2012; 51 Zölzer (10.1016/j.mrrev.2017.07.002_bib0265) 2015; 147 Henschel (10.1016/j.mrrev.2017.07.002_bib0330) 2012; 57 Natarajan (10.1016/j.mrrev.2017.07.002_bib0335) 1996; 104 Markunas (10.1016/j.mrrev.2017.07.002_bib0355) 2014; 122 Esteller (10.1016/j.mrrev.2017.07.002_bib0295) 2002; 196 Doudoroff (10.1016/j.mrrev.2017.07.002_bib0010) 1940; 23 Zaichkina (10.1016/j.mrrev.2017.07.002_bib0110) 2016; 161 Bae (10.1016/j.mrrev.2017.07.002_bib0170) 2015; 35 Shi (10.1016/j.mrrev.2017.07.002_bib0145) 2016; 151 Sanz (10.1016/j.mrrev.2017.07.002_bib0400) 2010; 11 Fenech (10.1016/j.mrrev.2017.07.002_bib0475) 1985; 147 Rossnerova (10.1016/j.mrrev.2017.07.002_bib0540) 2011; 708 Lindahl (10.1016/j.mrrev.2017.07.002_bib0025) 1988; 57 Siroux (10.1016/j.mrrev.2017.07.002_bib0530) 2016; 25 Morohoshi (10.1016/j.mrrev.2017.07.002_bib0030) 1993; 175 Guidelines (10.1016/j.mrrev.2017.07.002_bib0245) 2010 Nersesyan (10.1016/j.mrrev.2017.07.002_bib0455) 2016; 770 Øller (10.1016/j.mrrev.2017.07.002_bib0140) 2016; 31 Hemminki (10.1016/j.mrrev.2017.07.002_bib0325) 2014; 24 Dobzhansky (10.1016/j.mrrev.2017.07.002_bib0005) 1968 Bird (10.1016/j.mrrev.2017.07.002_bib0405) 2002; 16 McMichael (10.1016/j.mrrev.2017.07.002_bib0310) 1988; 48 Speit (10.1016/j.mrrev.2017.07.002_bib0465) 2013; 28 Vrijens (10.1016/j.mrrev.2017.07.002_bib0515) 2015; 123 Guo (10.1016/j.mrrev.2017.07.002_bib0395) 2014; 511 Evans (10.1016/j.mrrev.2017.07.002_bib0470) 1959; 1 Moran (10.1016/j.mrrev.2017.07.002_bib0495) 2016; 8 Seisenberger (10.1016/j.mrrev.2017.07.002_bib0410) 2013; 368 Sokolov (10.1016/j.mrrev.2017.07.002_bib0165) 2016; 17 Bateson (10.1016/j.mrrev.2017.07.002_bib0450) 2014; 592 Jelinek (10.1016/j.mrrev.2017.07.002_bib0060) 1988; 9 Davis (10.1016/j.mrrev.2017.07.002_bib0155) 2015; 184 Sram (10.1016/j.mrrev.2017.07.002_bib0460) 2016; 770 Brozmanova (10.1016/j.mrrev.2017.07.002_bib0050) 1990; 18 Bernal (10.1016/j.mrrev.2017.07.002_bib0180) 2013; 27 Rossnerova (10.1016/j.mrrev.2017.07.002_bib0190) 2009; 5-6 Pacchierotti (10.1016/j.mrrev.2017.07.002_bib0080) 2015 Hillman (10.1016/j.mrrev.2017.07.002_bib0440) 2015; 10 Gourabi (10.1016/j.mrrev.2017.07.002_bib0120) 1998; 13 Ko (10.1016/j.mrrev.2017.07.002_bib0320) 2014; WJG 20 Stevens (10.1016/j.mrrev.2017.07.002_bib0390) 2013; 23 Wojcik (10.1016/j.mrrev.2017.07.002_bib0160) 2000; 6 Dimova (10.1016/j.mrrev.2017.07.002_bib0015) 2008; 31 Committee on the Epidemiology of Air Pollutants (10.1016/j.mrrev.2017.07.002_bib0305) 1985 |
| References_xml | – year: 2009 ident: bib0280 article-title: WHO handbook on indoor radon, a public health perspectives, in: Health effect of radon, Chapter 1, The WHO European Centre for Environmental and Health Bonn Office – start-page: 127 year: 1985 end-page: 164 ident: bib0305 article-title: Book: Epidemiology and air pollution, Chapter 4: Concepts and strategies in planning epidemiologic studies on air pollution – volume: 49 start-page: e322 year: 2017 ident: bib0430 article-title: DNA methylation: an epigenetic mark of cellular memory publication-title: Exp. Mol. Med. – volume: 13 start-page: 475 year: 1998 end-page: 480 ident: bib0120 article-title: A cytokinesis-blocked micronucleus study of the radioadaptive response of lymphocytes of individuals occupationally exposed to chronic doses of radiation publication-title: Mutagenesis – volume: 7 start-page: 1 year: 2008 end-page: 7 ident: bib0095 article-title: Hormesis defined publication-title: Ageing Res. Rev. – volume: 57 start-page: 133 year: 1988 end-page: 157 ident: bib0025 article-title: Regulation and expression of the adaptive response to alkylating agents publication-title: Ann. Rev. Biochem. – start-page: 1 year: 2015 end-page: 23 ident: bib0080 article-title: Environmental impact on DNA methylation in the germline: State of the art and gaps of knowledge publication-title: Biomed. Res. Int. – start-page: 115 year: 2016 ident: bib0230 article-title: Clues to adaptation of humans to air pollution −a review of findings from Czech biomonitoring studies publication-title: EEMGS Annual Meeting – volume: 11 start-page: 1 year: 2010 end-page: 4 ident: bib0400 article-title: Genome-wide DNA demethylation in mammals publication-title: Genome Biol. – volume: 770 start-page: 1 year: 2016 end-page: 11 ident: bib0455 article-title: Use of the lymphocyte cytokinesis-block micronucleus assay in occupational biomonitoring of genome damage caused by publication-title: Mutat. Res. – volume: 44 start-page: 207 year: 1983 end-page: 219 ident: bib0105 article-title: Radiation hormesis, public health, and public policy: a commentary publication-title: Health Phys – volume: 10 start-page: 50 year: 2015 end-page: 61 ident: bib0440 article-title: Novel DNA methylation profiles associated with key gene regulation and transcription pathways in blood and placenta of growth-restricted neonates publication-title: Epigenetics – volume: 147 start-page: 29 year: 1985 end-page: 36 ident: bib0475 article-title: Measurement of micronuclei in lymphocytes publication-title: Mutat. Res. – volume: 11 start-page: 191 year: 2010 end-page: 203 ident: bib0490 article-title: Principles and challenges of genome-wide DNA methylation analysis publication-title: Nat. Rev. Genet. – start-page: 1 year: 2013 end-page: 12 ident: bib0535 article-title: The European hot spot B[a]P and PM publication-title: ISRN Public Health – volume: 8 start-page: 389 year: 2016 end-page: 399 ident: bib0495 article-title: Validation of a DNA methylation microarray for 850,000 CpG sites of the human genome enriched in enhancer sequences publication-title: Epigenomics – volume: 111 start-page: 1007 year: 2003 end-page: 1019 ident: bib0315 article-title: Environmental pollutants and breast cancer publication-title: Environ. Health Perspect. – volume: 49 start-page: 1 year: 2014 end-page: 19 ident: bib0385 article-title: Epigenetics across the human lifespan publication-title: Front. Cell Dev. Biol. – volume: 24 start-page: 64 year: 2014 end-page: 71 ident: bib0325 article-title: Cancer in immigrants as a pointer to the causes of cancer publication-title: Eur. J. Public Health – volume: 23 start-page: 1541 year: 2013 end-page: 1553 ident: bib0390 article-title: Estimating absolute methylation levels at single-CpG resolution from methylation enrichment and restriction enzyme sequencing methods publication-title: Genome Res. – volume: 717 start-page: 9 year: 2011 end-page: 16 ident: bib0085 article-title: Dose-responsiveness and persistence of microRNA expression alterations induced by cigarette smoke in mouse lung publication-title: Mutat. Res. – volume: 7 start-page: 1259 year: 2015 end-page: 1274 ident: bib0370 article-title: Associative DNA methylation changes in children with prenatal alcohol exposure publication-title: Epigenomics – volume: 31 start-page: 281 year: 2016 end-page: 289 ident: bib0140 article-title: Are organisms adapting to ionizing radiation at Chernobyl? publication-title: Trends Eco. Elvol. – volume: 57 start-page: 757 year: 2012 end-page: 768 ident: bib0330 article-title: Air pollution interventions and their impact on public health publication-title: Int. J. Public Health – volume: 770 start-page: 160 year: 2016 end-page: 169 ident: bib0460 article-title: Systematic review of the use of the lymphocyte cytokinesis-block micronucleus assay to measure DNA damage induced by exposure to polycyclic aromatic hydrocarbons publication-title: Mutat. Res. – volume: 7 start-page: 104 year: 2009 end-page: 131 ident: bib0175 article-title: Radiation-stimulated epigenetic reprogramming, of adaptive-response genes in the lung: an evolutionary gift for mounting adaptive protection against lung cancer publication-title: Dose Response – volume: 3 start-page: 1 year: 2017 end-page: 15 ident: bib0275 article-title: Micronucleus frequency and content in healthy relatives of cancer patients publication-title: Biomarkers – volume: 16 start-page: 6 year: 2002 end-page: 21 ident: bib0405 article-title: DNA methylation patterns and epigenetic memory publication-title: Genes & Develop. – volume: 175 start-page: 6010 year: 1993 end-page: 6017 ident: bib0030 article-title: Bacillus subtilis alkA gene encoding inducible 3-methyladenine DNA glycosylase is adjacent to the ada operon publication-title: J.Bacteriol. – volume: 40 start-page: 349 year: 1993 end-page: 357 ident: bib0290 article-title: Novel biomarkers of genetic damage in humans: use of fluorescence in situ hybridization to detect aneuploidy and micronuclei in exfoliated cells publication-title: J. Toxicol. Environ. Health – volume: 161 start-page: 24 year: 2016 end-page: 27 ident: bib0110 article-title: Induction of the adaptive response in mice exposed to He-Ne laser and X-ray radiation publication-title: Bull. Exp. Biol. Med. – year: 2012 ident: bib0235 article-title: IARC monographs on the evaluation of the cytogenetic risk of chemicals to humans, in: Chemical Agents and Related Occupations – volume: 25 start-page: 63 year: 2007 end-page: 75 ident: bib0135 article-title: Effects of cobalt-60 exposure on health of Taiwan residents suggest new approach needed in radiation protection publication-title: Dose Response – volume: 5 start-page: 435 year: 2009 end-page: 444 ident: bib0065 article-title: Polychlorinated biphenyls and Hudson River white perch: implications for population-level ecological risk assessment and risk management publication-title: Integr. Environ. Assess Manag. – volume: 594 start-page: 20 year: 2006 end-page: 29 ident: bib0240 article-title: The effects of exposure to different clastogens on the pattern of chromosomal aberrations detected by FISH whole chromosome painting in occupationally exposed individuals publication-title: Mutat. Res. – volume: 35 start-page: 227 year: 2015 end-page: 237 ident: bib0170 article-title: Low-dose ƴ-irradiation induces dual radio-adaptive responses depending on the post-irradiation time by altering microRNA expression profiles in normal human dermal fibroblasts publication-title: Int. J. Mol. Med. – volume: 32 start-page: 1544 year: 2015 end-page: 1555 ident: bib0075 article-title: Human adaptation to arsenic-rich environments publication-title: Mol. Biol. Evol. – volume: 13 start-page: 475 year: 1998 end-page: 480 ident: bib0350 article-title: A cytokinesis-blocked micronucleus study of the radioadaptive response of lymphocytes of individuals occupationally exposed to chronic doses of radiation publication-title: Mutagenesis – volume: 32 start-page: 453 year: 2014 end-page: 461 ident: bib0520 article-title: Detecting and characterizing circular RNAs publication-title: Nat. Biotechnol. – start-page: 333 year: 2013 end-page: 350 ident: bib0415 article-title: Biochemistry, genetics and molecular biology, Chapter 13: The mechanisms of epigenetic modification during DNA replication publication-title: INTECH – volume: 196 start-page: 1 year: 2002 end-page: 7 ident: bib0295 article-title: Cancer as an epigenetic disease: DNA methylation and chromatin alterations in human tumors publication-title: J. Pathol. – volume: 28 start-page: 375 year: 2013 end-page: 380 ident: bib0465 article-title: Does the recommended lymphocyte cytokinesis-block micronucleus assay for human biomonitoring actually detect DNA damage induced by occupational and environmental exposure to genotoxic chemicals? publication-title: Mutagenesis – volume: 24 start-page: 2349 year: 2015 end-page: 2359 ident: bib0425 article-title: Dynamics of smoking-induced genome-wide methylation changes with time since smoking cessation publication-title: Hum. Mol. Genet. – volume: 44 start-page: 272 year: 1998 end-page: 276 ident: bib0115 article-title: Effect of continuous gamma irradiation at a very low dose on the life span of mice publication-title: Gerontology – volume: 184 start-page: 56 year: 2015 end-page: 65 ident: bib0155 article-title: Solid Cancer Incidence in the Techa River Incidence Cohort: 1956-2007 publication-title: Radiat. Res. – volume: 5-6 start-page: 37 year: 2009 end-page: 41 ident: bib0190 article-title: Micronuclei frequency measured by automated image analysis as a biomarker of air pollution exposure publication-title: Ochrana Ovzdusi – volume: 793 start-page: 32 year: 2016 end-page: 40 ident: bib0270 article-title: Mapping the factors affecting the frequency and types of micronuclei in an elderly population from Southern Bohemia publication-title: Mutat. Res. – volume: 293 start-page: 455 year: 1995 end-page: 466 ident: bib0345 article-title: A unique metabolism of inorganic arsenic in native Andean women publication-title: Eur. J. Pharmacol. – volume: 741-742 start-page: 18 year: 2013 end-page: 26 ident: bib0225 article-title: Factors affecting the 27 publication-title: Mutat. Res. – volume: 5–6 start-page: 3 year: 2010 end-page: 7 ident: bib0210 article-title: Result of air pollution study ?new knowledge 2010 publication-title: Ochrana Ovzdusi – volume: 11 start-page: 241 year: 1988 end-page: 255 ident: bib0020 article-title: Adaptive response of Escherichia coli to alkylation damage publication-title: Environ. Mol. Mutagen. – volume: 23 start-page: 585 year: 1940 end-page: 611 ident: bib0010 article-title: Experiments on adaptation of Escherichia coli to sodium chloride publication-title: J. Gen. Physiol – volume: 780 start-page: 60 year: 2015 end-page: 70 ident: bib0220 article-title: Reduced gene expression levels after chronic exposure to high concentrations of air pollutants publication-title: Mutat. Res. – volume: 88 start-page: 112 year: 2016 end-page: 122 ident: bib0500 article-title: Newborns health in the Danube Region: Environment, biomonitoring, interventions and economic benefits in a large prospective birth cohort study publication-title: Environ. Int. – volume: 28 start-page: 105 year: 2016 end-page: 110 ident: bib0505 article-title: Noninvasive prenatal testing beyond genomic analysis: what the future holds publication-title: Curr. Opin. Obstet. Gynecol. – volume: 368 start-page: 20110330 year: 2013 ident: bib0410 article-title: Reprogramming DNA methylation in the mammalian life cycle: building and breaking epigenetic barriers publication-title: Phil. Trans. R. Soc. B – volume: 9 start-page: e107653 year: 2014 ident: bib0380 article-title: DNA methylation signatures triggered by prenatal maternal stress exposure to a natural disaster: Project Ice Storm publication-title: PLoS One – volume: 44 start-page: 1211 year: 2015 end-page: 1223 ident: bib0445 article-title: Early gestation as the critical time-window for changes in the prenatal environment to affect the adult human blood methylome publication-title: Int. J. Epidemiol. – volume: 203 start-page: 405 year: 1988 end-page: 414 ident: bib0285 article-title: Kinetochore immunofluorence in micronuclei: a rapid method for the in situ detection of aneuploidy and chromosome breakage in human fibroblasts publication-title: Mutat. Res. – volume: 31 start-page: 2241 year: 2017 end-page: 2251 ident: bib0420 article-title: Epigenetic memory in response to environmental stressors publication-title: FASEB J. – volume: 1 start-page: 216 year: 1959 end-page: 229 ident: bib0470 article-title: The relative biological efficiency of single doses of fast neutrons and gamma-rays on publication-title: Int. J. Radiat. Biol. – volume: 151 start-page: 537 year: 2016 end-page: 546 ident: bib0145 article-title: No adaptive response is induced by chronic low-dose radiation from Ra-226 in the CHSE/F fish embryonic cell line and the HaCaT human epithelial cell line publication-title: Environ. Res. – volume: 18 start-page: 331 year: 1990 end-page: 335 ident: bib0050 article-title: Expression of the publication-title: Nucl. Acids Res. – volume: 48 start-page: 751 year: 1988 end-page: 756 ident: bib0310 article-title: Cancer in migrants to Australia: Extending the descriptive epidemiological data publication-title: Cancer Res. – volume: 217 start-page: 601 year: 2014 end-page: 627 ident: bib0090 article-title: The effects of environmental chemical carcinogens on the microRNA machinery publication-title: Int. J. Hyg. Environ. Health – volume: 107 start-page: 475 year: 1999 end-page: 480 ident: bib0435 article-title: Fetal growth and maternal exposure to particulate matter during pregnancy publication-title: Environ. Health Perspect. – volume: 31 start-page: 396 year: 2008 end-page: 408 ident: bib0015 article-title: Adaptive response −Some underlying mechanisms and open questions publication-title: Genet. Mol. Biol. – start-page: 1 year: 1968 end-page: 34 ident: bib0005 article-title: Evolutionary biology: On some fundamental concept of Darwinian biology – volume: 136 start-page: 288 year: 2012 end-page: 294 ident: bib0250 article-title: Persistence of genetic damage in lymphocytes from former uranium miners publication-title: Cytogenet. Genome Res. – volume: 121 start-page: 971 year: 2013 end-page: 977 ident: bib0360 article-title: Differential DNA methylation in umbilical cord blood of infants exposed to low levels of arsenic in utero publication-title: Environ. Health Perspect. – volume: 27 start-page: 665 year: 2013 end-page: 671 ident: bib0180 article-title: Adaptive radiation-induced epigenetic alterations mitigated by antioxidants publication-title: FASEB J. – volume: 143 start-page: 97 year: 2015 end-page: 106 ident: bib0365 article-title: Prenatal arsenic exposur and the epigenome: Identifying sites of 5-methyl cytosine alterations that predict functional changes in gene expression in newborn cord blood and subsequent birth outcomes publication-title: Toxicol. Sci. – volume: 17 start-page: 1 year: 2016 end-page: 18 ident: bib0165 article-title: Global Gene Expression Alterations as a Crucial Constituent of Human Cell Response to Low Doses of Ionizing Radiation Exposure publication-title: Int. J. Mol. Sci. – volume: 122 start-page: 1147 year: 2014 end-page: 1153 ident: bib0355 article-title: Identification of DNA methylation changes in newborns related to maternal smoking during pregnancy publication-title: Environ. Health Perspect. – volume: 2 start-page: e276 year: 2015 end-page: 281 ident: bib0150 article-title: Ionizing radiation and risk of death from leukaemia and lymphoma in radiation-monitored workers (INWORKS): an international cohort study publication-title: Lancet Haematol. – volume: 26 start-page: 169 year: 2011 end-page: 175 ident: bib0205 article-title: Automated scoring of lymphocyte micronuclei by the MetaSystems Metafer image cytometry system and its application in studies of human mutagen sensitivity and biodosimetry of genotoxin exposure publication-title: Mutagenesis – volume: 28 start-page: 97 year: 2013 end-page: 106 ident: bib0200 article-title: Analysis of biomarkers in a Czech population exposed to heavy air pollution. Part II: chromosomal aberrations and oxidative stress publication-title: Mutagenesis – volume: 10 start-page: 595 year: 2011 end-page: 602 ident: bib0035 article-title: The ada operon of Mycobacterium tuberculosis encodes two DNA methyltransferases for inducible repair of DNA alkylation damage publication-title: DNA Repair – volume: 104 start-page: 445 year: 1996 end-page: 448 ident: bib0335 article-title: Current cytogenetic methods for detecting exposure and effects of mutagens and carcinogens publication-title: Environ. Health Perspect. – volume: 9 start-page: 81 year: 1988 end-page: 87 ident: bib0060 article-title: Transfection of murine multi-potent haemopoietic stem cells with an E. coli DNA alkyltransferase gene confers resistance to the toxic effects of alkylating agents publication-title: Carcinogenesis – volume: 43 start-page: 242 year: 2015 end-page: 246 ident: bib0100 article-title: Radiation Hormesis: Historical and Current Perspectives publication-title: J. Nucl. Med. Technol. – volume: 273 start-page: 271 year: 1992 end-page: 280 ident: bib0055 article-title: Increased resistence to the toxic effects of alkylating in tobacco expressing the publication-title: Mutat. Res. – volume: 512 start-page: 67 year: 2002 end-page: 84 ident: bib0045 article-title: Molecular mechanisms of adaptive response to alkylating agents in Escherichia coli and some remarks on O publication-title: Mutat. Res. – volume: 592 start-page: 2357 year: 2014 end-page: 2368 ident: bib0450 article-title: The biology of developmental plasticity and the predictive adaptive response hypothesis publication-title: J. Physiol. – volume: 51 start-page: 277 year: 2012 end-page: 282 ident: bib0255 article-title: Micronuclei in lymphocytes from currently active uranium miners publication-title: Radiat. Environ. Biophys. – volume: 511 start-page: 606 year: 2014 end-page: 610 ident: bib0395 article-title: The DNA methylation landscape of human early embryos publication-title: Nature – volume: 713 start-page: 76 year: 2011 end-page: 82 ident: bib0215 article-title: Expression of publication-title: Mutat. Res. – volume: 80 start-page: 175 year: 1977 end-page: 183 ident: bib0485 article-title: Analysis of calf-thymus satellite DNA: evidence for specific methylation of cytosine in C-G sequences publication-title: Eur. J. Biochem. – volume: 173 start-page: 3656 year: 1991 end-page: 3662 ident: bib0040 article-title: A weak adaptive response to alkylation damage in Salmonella typhimurium publication-title: J. Bacteriol. – volume: 123 start-page: 399 year: 2015 end-page: 411 ident: bib0515 article-title: MicroRNAs as potential signatures of environmental exposure or effect: a systematic review publication-title: Environ. Health Perspect. – volume: 105 start-page: 17046 year: 2008 end-page: 17049 ident: bib0375 article-title: Persistent epigenetic differences associated with prenatal exposure to famine in humans publication-title: PNAS – volume: 331 start-page: 1322 year: 2011 end-page: 1325 ident: bib0070 article-title: Mechanistic basis of resistance to PCBs in Atlantic tomcod from the Hudson River publication-title: Science – volume: 19 start-page: 321 year: 1966 end-page: 324 ident: bib0300 article-title: Studies of disease among migrants and native populations in Great Britain, Norway, and the United States: Prevalence of cardiorespiratory symptoms among migrants and native-born in the United States publication-title: Nat. Cancer Inst. Monogr. – volume: 28 start-page: 89 year: 2013 end-page: 95 ident: bib0195 article-title: Analysis of biomarkers in a Czech population exposed to heavy air pollution. Part I: bulky DNA adducts publication-title: Mutagenesis – volume: 669 start-page: 42 year: 2009 end-page: 47 ident: bib0185 article-title: The impact of air pollution on the levels of micronuclei measured by automated image analysis publication-title: Mutat. Res. – volume: 86 start-page: 629 year: 2013 end-page: 633 ident: bib0260 article-title: Micronuclei in lymphocytes from radon spa personnel in the Czech Republic publication-title: Int. Arch. Occup. Environ. Health – volume: 6 start-page: 252 year: 2008 end-page: 271 ident: bib0125 article-title: Evidence for radiation hormesis after publication-title: Dose Response – volume: 6 start-page: 281 year: 2000 end-page: 300 ident: bib0160 article-title: The current status of the adaptive response to ionizing radiation in mammalian cells publication-title: Human and Ecol. Risk Asses. – volume: 25 start-page: 124 year: 2016 end-page: 129 ident: bib0530 article-title: The exposome concept: a challenge and a potential driver for environmental health research publication-title: Eur. Respir. Rev. – volume: 370 start-page: 151 year: 1996 end-page: 158 ident: bib0340 article-title: Chromosomal aberrations in peripheral blood lymphocytes from native Andrean women and children from northwestern Argentina exposed to arsenic in drinking water publication-title: Mutat. Res. – volume: 14 start-page: 1847 year: 2005 end-page: 1850 ident: bib0525 article-title: Complementing the Genome with an Exposome: The Outstanding Challenge of Environmental Exposure Measurement in Molecular Epidemiology publication-title: Cancer Epidemiol. Biomarkers Prev. – year: 2010 ident: bib0245 article-title: WHO Guidelines for Indoor Air Quality: Selected Pollutants, The WHO European Centre for Environmental and Health Bonn Office – volume: WJG 20 start-page: 1238 year: 2014 end-page: 1247 ident: bib0320 publication-title: Epidemiological studies of migration and environmental risk factors in the inflammatory bowel diseases – volume: 12 start-page: 230 year: 2015 end-page: 232 ident: bib0510 article-title: Coverage recommendations for methylation analysis by whole-genome bisulfite sequencing publication-title: Nature Methods – volume: 147 start-page: 17 year: 2015 end-page: 23 ident: bib0265 article-title: Analysis of genetic damage in lymphocytes of former uranium processing workers publication-title: Cytogenet. Genome Res. – volume: 216 start-page: 541 year: 2013 end-page: 552 ident: bib0480 article-title: HUMN project initiative and review of validation, quality control and prospects for further development of automated micronucleus assays using image cytometry systems publication-title: Int. J. Hyg. Environ. Health – volume: 30 start-page: 663 year: 2015 end-page: 676 ident: bib0130 article-title: Radio-adaptive response of base excision repair genes and proteins in human peripheral blood mononuclear cells exposed to gamma radiation publication-title: Mutagenesis – volume: 708 start-page: 44 year: 2011 end-page: 49 ident: bib0540 article-title: Factors affecting the frequency of micronuclei in asthmatic and healthy children from Ostrava publication-title: Mutat. Res. – volume: 11 start-page: 241 year: 1988 ident: 10.1016/j.mrrev.2017.07.002_bib0020 article-title: Adaptive response of Escherichia coli to alkylation damage publication-title: Environ. Mol. Mutagen. doi: 10.1002/em.2850110210 – volume: 11 start-page: 1 year: 2010 ident: 10.1016/j.mrrev.2017.07.002_bib0400 article-title: Genome-wide DNA demethylation in mammals publication-title: Genome Biol. doi: 10.1186/gb-2010-11-3-110 – volume: 111 start-page: 1007 year: 2003 ident: 10.1016/j.mrrev.2017.07.002_bib0315 article-title: Environmental pollutants and breast cancer publication-title: Environ. Health Perspect. doi: 10.1289/ehp.6310 – start-page: 1 year: 2013 ident: 10.1016/j.mrrev.2017.07.002_bib0535 article-title: The European hot spot B[a]P and PM2.5 exposure −The Ostrava Region, Czech Republic : Health research results publication-title: ISRN Public Health doi: 10.1155/2013/416701 – volume: 31 start-page: 281 year: 2016 ident: 10.1016/j.mrrev.2017.07.002_bib0140 article-title: Are organisms adapting to ionizing radiation at Chernobyl? publication-title: Trends Eco. Elvol. doi: 10.1016/j.tree.2016.01.005 – volume: 741-742 start-page: 18 year: 2013 ident: 10.1016/j.mrrev.2017.07.002_bib0225 article-title: Factors affecting the 27K DNA methylation pattern in asthmatic and healthy children from locations with various environments publication-title: Mutat. Res. doi: 10.1016/j.mrfmmm.2013.02.003 – volume: 122 start-page: 1147 year: 2014 ident: 10.1016/j.mrrev.2017.07.002_bib0355 article-title: Identification of DNA methylation changes in newborns related to maternal smoking during pregnancy publication-title: Environ. Health Perspect. doi: 10.1289/ehp.1307892 – volume: 770 start-page: 1 issue: PtA year: 2016 ident: 10.1016/j.mrrev.2017.07.002_bib0455 article-title: Use of the lymphocyte cytokinesis-block micronucleus assay in occupational biomonitoring of genome damage caused by in vivo exposure to chemical genotoxins: Past, present and future publication-title: Mutat. Res. doi: 10.1016/j.mrrev.2016.05.003 – volume: 123 start-page: 399 year: 2015 ident: 10.1016/j.mrrev.2017.07.002_bib0515 article-title: MicroRNAs as potential signatures of environmental exposure or effect: a systematic review publication-title: Environ. Health Perspect. doi: 10.1289/ehp.1408459 – volume: 13 start-page: 475 year: 1998 ident: 10.1016/j.mrrev.2017.07.002_bib0350 article-title: A cytokinesis-blocked micronucleus study of the radioadaptive response of lymphocytes of individuals occupationally exposed to chronic doses of radiation publication-title: Mutagenesis doi: 10.1093/mutage/13.5.475 – volume: 217 start-page: 601 year: 2014 ident: 10.1016/j.mrrev.2017.07.002_bib0090 article-title: The effects of environmental chemical carcinogens on the microRNA machinery publication-title: Int. J. Hyg. Environ. Health doi: 10.1016/j.ijheh.2014.01.001 – volume: 196 start-page: 1 year: 2002 ident: 10.1016/j.mrrev.2017.07.002_bib0295 article-title: Cancer as an epigenetic disease: DNA methylation and chromatin alterations in human tumors publication-title: J. Pathol. doi: 10.1002/path.1024 – volume: 9 start-page: 81 year: 1988 ident: 10.1016/j.mrrev.2017.07.002_bib0060 article-title: Transfection of murine multi-potent haemopoietic stem cells with an E. coli DNA alkyltransferase gene confers resistance to the toxic effects of alkylating agents publication-title: Carcinogenesis doi: 10.1093/carcin/9.1.81 – volume: 57 start-page: 133 year: 1988 ident: 10.1016/j.mrrev.2017.07.002_bib0025 article-title: Regulation and expression of the adaptive response to alkylating agents publication-title: Ann. Rev. Biochem. doi: 10.1146/annurev.bi.57.070188.001025 – volume: 30 start-page: 663 year: 2015 ident: 10.1016/j.mrrev.2017.07.002_bib0130 article-title: Radio-adaptive response of base excision repair genes and proteins in human peripheral blood mononuclear cells exposed to gamma radiation publication-title: Mutagenesis doi: 10.1093/mutage/gev032 – volume: 7 start-page: 104 year: 2009 ident: 10.1016/j.mrrev.2017.07.002_bib0175 article-title: Radiation-stimulated epigenetic reprogramming, of adaptive-response genes in the lung: an evolutionary gift for mounting adaptive protection against lung cancer publication-title: Dose Response doi: 10.2203/dose-response.08-016.Scott – volume: 32 start-page: 1544 year: 2015 ident: 10.1016/j.mrrev.2017.07.002_bib0075 article-title: Human adaptation to arsenic-rich environments publication-title: Mol. Biol. Evol. doi: 10.1093/molbev/msv046 – volume: 17 start-page: 1 year: 2016 ident: 10.1016/j.mrrev.2017.07.002_bib0165 article-title: Global Gene Expression Alterations as a Crucial Constituent of Human Cell Response to Low Doses of Ionizing Radiation Exposure publication-title: Int. J. Mol. Sci. – volume: 3 start-page: 1 year: 2017 ident: 10.1016/j.mrrev.2017.07.002_bib0275 article-title: Micronucleus frequency and content in healthy relatives of cancer patients publication-title: Biomarkers doi: 10.1080/1354750X.2016.1276627 – start-page: 1 year: 2015 ident: 10.1016/j.mrrev.2017.07.002_bib0080 article-title: Environmental impact on DNA methylation in the germline: State of the art and gaps of knowledge publication-title: Biomed. Res. Int. doi: 10.1155/2015/123484 – volume: 14 start-page: 1847 year: 2005 ident: 10.1016/j.mrrev.2017.07.002_bib0525 article-title: Complementing the Genome with an Exposome: The Outstanding Challenge of Environmental Exposure Measurement in Molecular Epidemiology publication-title: Cancer Epidemiol. Biomarkers Prev. doi: 10.1158/1055-9965.EPI-05-0456 – volume: 26 start-page: 169 year: 2011 ident: 10.1016/j.mrrev.2017.07.002_bib0205 article-title: Automated scoring of lymphocyte micronuclei by the MetaSystems Metafer image cytometry system and its application in studies of human mutagen sensitivity and biodosimetry of genotoxin exposure publication-title: Mutagenesis doi: 10.1093/mutage/geq057 – volume: 1 start-page: 216 year: 1959 ident: 10.1016/j.mrrev.2017.07.002_bib0470 article-title: The relative biological efficiency of single doses of fast neutrons and gamma-rays on Vicia faba roots and the effect of oxygen. Part II. Chromosome damage: the production of micronuclei publication-title: Int. J. Radiat. Biol. – volume: 80 start-page: 175 year: 1977 ident: 10.1016/j.mrrev.2017.07.002_bib0485 article-title: Analysis of calf-thymus satellite DNA: evidence for specific methylation of cytosine in C-G sequences publication-title: Eur. J. Biochem. doi: 10.1111/j.1432-1033.1977.tb11869.x – volume: 25 start-page: 63 year: 2007 ident: 10.1016/j.mrrev.2017.07.002_bib0135 article-title: Effects of cobalt-60 exposure on health of Taiwan residents suggest new approach needed in radiation protection publication-title: Dose Response – volume: 5 start-page: 435 year: 2009 ident: 10.1016/j.mrrev.2017.07.002_bib0065 article-title: Polychlorinated biphenyls and Hudson River white perch: implications for population-level ecological risk assessment and risk management publication-title: Integr. Environ. Assess Manag. doi: 10.1897/IEAM_2008-080.1 – volume: 9 start-page: e107653 year: 2014 ident: 10.1016/j.mrrev.2017.07.002_bib0380 article-title: DNA methylation signatures triggered by prenatal maternal stress exposure to a natural disaster: Project Ice Storm publication-title: PLoS One doi: 10.1371/journal.pone.0107653 – volume: 57 start-page: 757 year: 2012 ident: 10.1016/j.mrrev.2017.07.002_bib0330 article-title: Air pollution interventions and their impact on public health publication-title: Int. J. Public Health doi: 10.1007/s00038-012-0369-6 – volume: 32 start-page: 453 year: 2014 ident: 10.1016/j.mrrev.2017.07.002_bib0520 article-title: Detecting and characterizing circular RNAs publication-title: Nat. Biotechnol. doi: 10.1038/nbt.2890 – volume: 25 start-page: 124 year: 2016 ident: 10.1016/j.mrrev.2017.07.002_bib0530 article-title: The exposome concept: a challenge and a potential driver for environmental health research publication-title: Eur. Respir. Rev. doi: 10.1183/16000617.0034-2016 – volume: 28 start-page: 89 year: 2013 ident: 10.1016/j.mrrev.2017.07.002_bib0195 article-title: Analysis of biomarkers in a Czech population exposed to heavy air pollution. Part I: bulky DNA adducts publication-title: Mutagenesis doi: 10.1093/mutage/ges057 – volume: 104 start-page: 445 year: 1996 ident: 10.1016/j.mrrev.2017.07.002_bib0335 article-title: Current cytogenetic methods for detecting exposure and effects of mutagens and carcinogens publication-title: Environ. Health Perspect. – volume: 273 start-page: 271 year: 1992 ident: 10.1016/j.mrrev.2017.07.002_bib0055 article-title: Increased resistence to the toxic effects of alkylating in tobacco expressing the E. coli DNA repair gene ada publication-title: Mutat. Res. doi: 10.1016/0921-8777(92)90089-L – volume: 6 start-page: 252 year: 2008 ident: 10.1016/j.mrrev.2017.07.002_bib0125 article-title: Evidence for radiation hormesis after in vitro exposure of human lymphocytes to low doses of ionizing radiation publication-title: Dose Response doi: 10.2203/dose-response.07-024.Rithidech – volume: 8 start-page: 389 year: 2016 ident: 10.1016/j.mrrev.2017.07.002_bib0495 article-title: Validation of a DNA methylation microarray for 850,000 CpG sites of the human genome enriched in enhancer sequences publication-title: Epigenomics doi: 10.2217/epi.15.114 – volume: 49 start-page: e322 year: 2017 ident: 10.1016/j.mrrev.2017.07.002_bib0430 article-title: DNA methylation: an epigenetic mark of cellular memory publication-title: Exp. Mol. Med. doi: 10.1038/emm.2017.10 – volume: 592 start-page: 2357 year: 2014 ident: 10.1016/j.mrrev.2017.07.002_bib0450 article-title: The biology of developmental plasticity and the predictive adaptive response hypothesis publication-title: J. Physiol. doi: 10.1113/jphysiol.2014.271460 – volume: 147 start-page: 29 year: 1985 ident: 10.1016/j.mrrev.2017.07.002_bib0475 article-title: Measurement of micronuclei in lymphocytes publication-title: Mutat. Res. doi: 10.1016/0165-1161(85)90015-9 – year: 2012 ident: 10.1016/j.mrrev.2017.07.002_bib0235 – volume: 18 start-page: 331 year: 1990 ident: 10.1016/j.mrrev.2017.07.002_bib0050 article-title: Expression of the E. coli ada gene in yeast protects against the toxic and mutagenic effects of N-methyl-N'-nitro-N-nitrosoguanidin publication-title: Nucl. Acids Res. doi: 10.1093/nar/18.2.331 – volume: 512 start-page: 67 year: 2002 ident: 10.1016/j.mrrev.2017.07.002_bib0045 article-title: Molecular mechanisms of adaptive response to alkylating agents in Escherichia coli and some remarks on O6-methylguanine DNA-methyltransferase in other organisms publication-title: Mutat. Res. doi: 10.1016/S1383-5742(02)00025-X – volume: 48 start-page: 751 year: 1988 ident: 10.1016/j.mrrev.2017.07.002_bib0310 article-title: Cancer in migrants to Australia: Extending the descriptive epidemiological data publication-title: Cancer Res. – volume: 12 start-page: 230 year: 2015 ident: 10.1016/j.mrrev.2017.07.002_bib0510 article-title: Coverage recommendations for methylation analysis by whole-genome bisulfite sequencing publication-title: Nature Methods doi: 10.1038/nmeth.3152 – volume: 203 start-page: 405 year: 1988 ident: 10.1016/j.mrrev.2017.07.002_bib0285 article-title: Kinetochore immunofluorence in micronuclei: a rapid method for the in situ detection of aneuploidy and chromosome breakage in human fibroblasts publication-title: Mutat. Res. doi: 10.1016/0165-1161(88)90013-1 – volume: 51 start-page: 277 year: 2012 ident: 10.1016/j.mrrev.2017.07.002_bib0255 article-title: Micronuclei in lymphocytes from currently active uranium miners publication-title: Radiat. Environ. Biophys. doi: 10.1007/s00411-012-0422-0 – volume: 717 start-page: 9 year: 2011 ident: 10.1016/j.mrrev.2017.07.002_bib0085 article-title: Dose-responsiveness and persistence of microRNA expression alterations induced by cigarette smoke in mouse lung publication-title: Mutat. Res. doi: 10.1016/j.mrfmmm.2010.12.008 – volume: 713 start-page: 76 year: 2011 ident: 10.1016/j.mrrev.2017.07.002_bib0215 article-title: Expression of XRCC5 in peripheral blood lymphocytes is upregulated in subjects from a heavily polluted region in the Czech Republic publication-title: Mutat. Res. doi: 10.1016/j.mrfmmm.2011.06.001 – year: 2010 ident: 10.1016/j.mrrev.2017.07.002_bib0245 – volume: 31 start-page: 396 year: 2008 ident: 10.1016/j.mrrev.2017.07.002_bib0015 article-title: Adaptive response −Some underlying mechanisms and open questions publication-title: Genet. Mol. Biol. doi: 10.1590/S1415-47572008000300002 – volume: 770 start-page: 160 issue: PtA year: 2016 ident: 10.1016/j.mrrev.2017.07.002_bib0460 article-title: Systematic review of the use of the lymphocyte cytokinesis-block micronucleus assay to measure DNA damage induced by exposure to polycyclic aromatic hydrocarbons publication-title: Mutat. Res. – volume: 6 start-page: 281 year: 2000 ident: 10.1016/j.mrrev.2017.07.002_bib0160 article-title: The current status of the adaptive response to ionizing radiation in mammalian cells publication-title: Human and Ecol. Risk Asses. doi: 10.1080/10807030009380063 – volume: 151 start-page: 537 year: 2016 ident: 10.1016/j.mrrev.2017.07.002_bib0145 article-title: No adaptive response is induced by chronic low-dose radiation from Ra-226 in the CHSE/F fish embryonic cell line and the HaCaT human epithelial cell line publication-title: Environ. Res. doi: 10.1016/j.envres.2016.08.026 – volume: 31 start-page: 2241 year: 2017 ident: 10.1016/j.mrrev.2017.07.002_bib0420 article-title: Epigenetic memory in response to environmental stressors publication-title: FASEB J. doi: 10.1096/fj.201601059RR – volume: 5-6 start-page: 37 year: 2009 ident: 10.1016/j.mrrev.2017.07.002_bib0190 article-title: Micronuclei frequency measured by automated image analysis as a biomarker of air pollution exposure publication-title: Ochrana Ovzdusi – volume: 23 start-page: 1541 year: 2013 ident: 10.1016/j.mrrev.2017.07.002_bib0390 article-title: Estimating absolute methylation levels at single-CpG resolution from methylation enrichment and restriction enzyme sequencing methods publication-title: Genome Res. doi: 10.1101/gr.152231.112 – start-page: 1 year: 1968 ident: 10.1016/j.mrrev.2017.07.002_bib0005 – year: 2009 ident: 10.1016/j.mrrev.2017.07.002_bib0280 – volume: 44 start-page: 207 year: 1983 ident: 10.1016/j.mrrev.2017.07.002_bib0105 article-title: Radiation hormesis, public health, and public policy: a commentary publication-title: Health Phys doi: 10.1097/00004032-198303000-00001 – volume: 331 start-page: 1322 year: 2011 ident: 10.1016/j.mrrev.2017.07.002_bib0070 article-title: Mechanistic basis of resistance to PCBs in Atlantic tomcod from the Hudson River publication-title: Science doi: 10.1126/science.1197296 – volume: 370 start-page: 151 year: 1996 ident: 10.1016/j.mrrev.2017.07.002_bib0340 article-title: Chromosomal aberrations in peripheral blood lymphocytes from native Andrean women and children from northwestern Argentina exposed to arsenic in drinking water publication-title: Mutat. Res. doi: 10.1016/S0165-1218(96)00060-2 – volume: 86 start-page: 629 year: 2013 ident: 10.1016/j.mrrev.2017.07.002_bib0260 article-title: Micronuclei in lymphocytes from radon spa personnel in the Czech Republic publication-title: Int. Arch. Occup. Environ. Health doi: 10.1007/s00420-012-0795-z – volume: 5–6 start-page: 3 year: 2010 ident: 10.1016/j.mrrev.2017.07.002_bib0210 article-title: Result of air pollution study ?new knowledge 2010 publication-title: Ochrana Ovzdusi – volume: 105 start-page: 17046 year: 2008 ident: 10.1016/j.mrrev.2017.07.002_bib0375 article-title: Persistent epigenetic differences associated with prenatal exposure to famine in humans publication-title: PNAS doi: 10.1073/pnas.0806560105 – volume: 780 start-page: 60 year: 2015 ident: 10.1016/j.mrrev.2017.07.002_bib0220 article-title: Reduced gene expression levels after chronic exposure to high concentrations of air pollutants publication-title: Mutat. Res. doi: 10.1016/j.mrfmmm.2015.08.001 – volume: 121 start-page: 971 year: 2013 ident: 10.1016/j.mrrev.2017.07.002_bib0360 article-title: Differential DNA methylation in umbilical cord blood of infants exposed to low levels of arsenic in utero publication-title: Environ. Health Perspect. doi: 10.1289/ehp.1205925 – volume: 24 start-page: 64 year: 2014 ident: 10.1016/j.mrrev.2017.07.002_bib0325 article-title: Cancer in immigrants as a pointer to the causes of cancer publication-title: Eur. J. Public Health doi: 10.1093/eurpub/cku102 – volume: 43 start-page: 242 year: 2015 ident: 10.1016/j.mrrev.2017.07.002_bib0100 article-title: Radiation Hormesis: Historical and Current Perspectives publication-title: J. Nucl. Med. Technol. doi: 10.2967/jnmt.115.166074 – volume: 35 start-page: 227 year: 2015 ident: 10.1016/j.mrrev.2017.07.002_bib0170 article-title: Low-dose ƴ-irradiation induces dual radio-adaptive responses depending on the post-irradiation time by altering microRNA expression profiles in normal human dermal fibroblasts publication-title: Int. J. Mol. Med. doi: 10.3892/ijmm.2014.1994 – volume: 7 start-page: 1 year: 2008 ident: 10.1016/j.mrrev.2017.07.002_bib0095 article-title: Hormesis defined publication-title: Ageing Res. Rev. doi: 10.1016/j.arr.2007.08.007 – volume: 161 start-page: 24 year: 2016 ident: 10.1016/j.mrrev.2017.07.002_bib0110 article-title: Induction of the adaptive response in mice exposed to He-Ne laser and X-ray radiation publication-title: Bull. Exp. Biol. Med. doi: 10.1007/s10517-016-3336-z – volume: 16 start-page: 6 year: 2002 ident: 10.1016/j.mrrev.2017.07.002_bib0405 article-title: DNA methylation patterns and epigenetic memory publication-title: Genes & Develop. doi: 10.1101/gad.947102 – start-page: 127 year: 1985 ident: 10.1016/j.mrrev.2017.07.002_bib0305 – volume: 23 start-page: 585 year: 1940 ident: 10.1016/j.mrrev.2017.07.002_bib0010 article-title: Experiments on adaptation of Escherichia coli to sodium chloride publication-title: J. Gen. Physiol doi: 10.1085/jgp.23.5.585 – volume: 28 start-page: 97 year: 2013 ident: 10.1016/j.mrrev.2017.07.002_bib0200 article-title: Analysis of biomarkers in a Czech population exposed to heavy air pollution. Part II: chromosomal aberrations and oxidative stress publication-title: Mutagenesis doi: 10.1093/mutage/ges058 – volume: 708 start-page: 44 year: 2011 ident: 10.1016/j.mrrev.2017.07.002_bib0540 article-title: Factors affecting the frequency of micronuclei in asthmatic and healthy children from Ostrava publication-title: Mutat. Res. doi: 10.1016/j.mrfmmm.2011.01.004 – volume: 13 start-page: 475 year: 1998 ident: 10.1016/j.mrrev.2017.07.002_bib0120 article-title: A cytokinesis-blocked micronucleus study of the radioadaptive response of lymphocytes of individuals occupationally exposed to chronic doses of radiation publication-title: Mutagenesis doi: 10.1093/mutage/13.5.475 – volume: 147 start-page: 17 year: 2015 ident: 10.1016/j.mrrev.2017.07.002_bib0265 article-title: Analysis of genetic damage in lymphocytes of former uranium processing workers publication-title: Cytogenet. Genome Res. doi: 10.1159/000441889 – volume: 107 start-page: 475 year: 1999 ident: 10.1016/j.mrrev.2017.07.002_bib0435 article-title: Fetal growth and maternal exposure to particulate matter during pregnancy publication-title: Environ. Health Perspect. doi: 10.1289/ehp.99107475 – volume: 10 start-page: 50 year: 2015 ident: 10.1016/j.mrrev.2017.07.002_bib0440 article-title: Novel DNA methylation profiles associated with key gene regulation and transcription pathways in blood and placenta of growth-restricted neonates publication-title: Epigenetics doi: 10.4161/15592294.2014.989741 – volume: 28 start-page: 375 year: 2013 ident: 10.1016/j.mrrev.2017.07.002_bib0465 article-title: Does the recommended lymphocyte cytokinesis-block micronucleus assay for human biomonitoring actually detect DNA damage induced by occupational and environmental exposure to genotoxic chemicals? publication-title: Mutagenesis doi: 10.1093/mutage/get026 – volume: 88 start-page: 112 year: 2016 ident: 10.1016/j.mrrev.2017.07.002_bib0500 article-title: Newborns health in the Danube Region: Environment, biomonitoring, interventions and economic benefits in a large prospective birth cohort study publication-title: Environ. Int. doi: 10.1016/j.envint.2015.12.009 – volume: 669 start-page: 42 year: 2009 ident: 10.1016/j.mrrev.2017.07.002_bib0185 article-title: The impact of air pollution on the levels of micronuclei measured by automated image analysis publication-title: Mutat. Res. doi: 10.1016/j.mrfmmm.2009.04.008 – volume: 216 start-page: 541 year: 2013 ident: 10.1016/j.mrrev.2017.07.002_bib0480 article-title: HUMN project initiative and review of validation, quality control and prospects for further development of automated micronucleus assays using image cytometry systems publication-title: Int. J. Hyg. Environ. Health doi: 10.1016/j.ijheh.2013.01.008 – volume: 511 start-page: 606 year: 2014 ident: 10.1016/j.mrrev.2017.07.002_bib0395 article-title: The DNA methylation landscape of human early embryos publication-title: Nature doi: 10.1038/nature13544 – volume: 27 start-page: 665 year: 2013 ident: 10.1016/j.mrrev.2017.07.002_bib0180 article-title: Adaptive radiation-induced epigenetic alterations mitigated by antioxidants publication-title: FASEB J. doi: 10.1096/fj.12-220350 – volume: 793 start-page: 32 year: 2016 ident: 10.1016/j.mrrev.2017.07.002_bib0270 article-title: Mapping the factors affecting the frequency and types of micronuclei in an elderly population from Southern Bohemia publication-title: Mutat. Res. doi: 10.1016/j.mrfmmm.2016.10.004 – volume: 28 start-page: 105 year: 2016 ident: 10.1016/j.mrrev.2017.07.002_bib0505 article-title: Noninvasive prenatal testing beyond genomic analysis: what the future holds publication-title: Curr. Opin. Obstet. Gynecol. doi: 10.1097/GCO.0000000000000252 – volume: 175 start-page: 6010 year: 1993 ident: 10.1016/j.mrrev.2017.07.002_bib0030 article-title: Bacillus subtilis alkA gene encoding inducible 3-methyladenine DNA glycosylase is adjacent to the ada operon publication-title: J.Bacteriol. doi: 10.1128/JB.175.18.6010-6017.1993 – volume: 184 start-page: 56 year: 2015 ident: 10.1016/j.mrrev.2017.07.002_bib0155 article-title: Solid Cancer Incidence in the Techa River Incidence Cohort: 1956-2007 publication-title: Radiat. Res. doi: 10.1667/RR14023.1 – volume: 10 start-page: 595 year: 2011 ident: 10.1016/j.mrrev.2017.07.002_bib0035 article-title: The ada operon of Mycobacterium tuberculosis encodes two DNA methyltransferases for inducible repair of DNA alkylation damage publication-title: DNA Repair doi: 10.1016/j.dnarep.2011.03.007 – volume: 7 start-page: 1259 year: 2015 ident: 10.1016/j.mrrev.2017.07.002_bib0370 article-title: Associative DNA methylation changes in children with prenatal alcohol exposure publication-title: Epigenomics doi: 10.2217/epi.15.60 – volume: 40 start-page: 349 year: 1993 ident: 10.1016/j.mrrev.2017.07.002_bib0290 article-title: Novel biomarkers of genetic damage in humans: use of fluorescence in situ hybridization to detect aneuploidy and micronuclei in exfoliated cells publication-title: J. Toxicol. Environ. Health doi: 10.1080/15287399309531800 – volume: 44 start-page: 272 year: 1998 ident: 10.1016/j.mrrev.2017.07.002_bib0115 article-title: Effect of continuous gamma irradiation at a very low dose on the life span of mice publication-title: Gerontology doi: 10.1159/000022024 – start-page: 115 year: 2016 ident: 10.1016/j.mrrev.2017.07.002_bib0230 article-title: Clues to adaptation of humans to air pollution −a review of findings from Czech biomonitoring studies publication-title: EEMGS Annual Meeting – volume: 24 start-page: 2349 year: 2015 ident: 10.1016/j.mrrev.2017.07.002_bib0425 article-title: Dynamics of smoking-induced genome-wide methylation changes with time since smoking cessation publication-title: Hum. Mol. Genet. doi: 10.1093/hmg/ddu751 – volume: 173 start-page: 3656 year: 1991 ident: 10.1016/j.mrrev.2017.07.002_bib0040 article-title: A weak adaptive response to alkylation damage in Salmonella typhimurium publication-title: J. Bacteriol. doi: 10.1128/JB.173.12.3656-3662.1991 – volume: 136 start-page: 288 year: 2012 ident: 10.1016/j.mrrev.2017.07.002_bib0250 article-title: Persistence of genetic damage in lymphocytes from former uranium miners publication-title: Cytogenet. Genome Res. doi: 10.1159/000338084 – volume: 293 start-page: 455 year: 1995 ident: 10.1016/j.mrrev.2017.07.002_bib0345 article-title: A unique metabolism of inorganic arsenic in native Andean women publication-title: Eur. J. Pharmacol. doi: 10.1016/0926-6917(95)90066-7 – volume: 368 start-page: 20110330 year: 2013 ident: 10.1016/j.mrrev.2017.07.002_bib0410 article-title: Reprogramming DNA methylation in the mammalian life cycle: building and breaking epigenetic barriers publication-title: Phil. Trans. R. Soc. B doi: 10.1098/rstb.2011.0330 – volume: 143 start-page: 97 year: 2015 ident: 10.1016/j.mrrev.2017.07.002_bib0365 article-title: Prenatal arsenic exposur and the epigenome: Identifying sites of 5-methyl cytosine alterations that predict functional changes in gene expression in newborn cord blood and subsequent birth outcomes publication-title: Toxicol. Sci. doi: 10.1093/toxsci/kfu210 – volume: 594 start-page: 20 year: 2006 ident: 10.1016/j.mrrev.2017.07.002_bib0240 article-title: The effects of exposure to different clastogens on the pattern of chromosomal aberrations detected by FISH whole chromosome painting in occupationally exposed individuals publication-title: Mutat. Res. doi: 10.1016/j.mrfmmm.2005.07.009 – volume: 49 start-page: 1 year: 2014 ident: 10.1016/j.mrrev.2017.07.002_bib0385 article-title: Epigenetics across the human lifespan publication-title: Front. Cell Dev. Biol. – volume: 19 start-page: 321 year: 1966 ident: 10.1016/j.mrrev.2017.07.002_bib0300 article-title: Studies of disease among migrants and native populations in Great Britain, Norway, and the United States: Prevalence of cardiorespiratory symptoms among migrants and native-born in the United States publication-title: Nat. Cancer Inst. Monogr. – start-page: 333 year: 2013 ident: 10.1016/j.mrrev.2017.07.002_bib0415 article-title: Biochemistry, genetics and molecular biology, Chapter 13: The mechanisms of epigenetic modification during DNA replication publication-title: INTECH – volume: 2 start-page: e276 year: 2015 ident: 10.1016/j.mrrev.2017.07.002_bib0150 article-title: Ionizing radiation and risk of death from leukaemia and lymphoma in radiation-monitored workers (INWORKS): an international cohort study publication-title: Lancet Haematol. doi: 10.1016/S2352-3026(15)00094-0 – volume: 11 start-page: 191 year: 2010 ident: 10.1016/j.mrrev.2017.07.002_bib0490 article-title: Principles and challenges of genome-wide DNA methylation analysis publication-title: Nat. Rev. Genet. doi: 10.1038/nrg2732 – volume: WJG 20 start-page: 1238 year: 2014 ident: 10.1016/j.mrrev.2017.07.002_bib0320 publication-title: Epidemiological studies of migration and environmental risk factors in the inflammatory bowel diseases – volume: 44 start-page: 1211 year: 2015 ident: 10.1016/j.mrrev.2017.07.002_bib0445 article-title: Early gestation as the critical time-window for changes in the prenatal environment to affect the adult human blood methylome publication-title: Int. J. Epidemiol. doi: 10.1093/ije/dyv043 |
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| SubjectTerms | Adaptation, Physiological - drug effects Adaptation, Physiological - radiation effects Adaptive response Air Pollution - adverse effects Benzo(a)pyrene - toxicity Chromosome Aberrations - drug effects Chromosome Aberrations - radiation effects Cytogenetics Czech Republic DNA Damage - drug effects DNA Damage - radiation effects DNA methylation DNA Methylation - drug effects DNA Methylation - radiation effects Environmental exposure Environmental Monitoring Humans Micronuclei Uranium - toxicity X-Rays - adverse effects |
| Title | Adaptation of the human population to the environment: Current knowledge, clues from Czech cytogenetic and “omics” biomonitoring studies and possible mechanisms |
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