Predictive Value of Endostatin in Chronic Heart Failure Patients with Poor Kidney Function

• Published in: Cardiology Vol. 130; no. 1; pp. 17 - 22
• Main Authors: Ueland, Thor, Aukrust, Pål, Nymo, Ståle H., Kjekshus, John, McMurray, John J.V., Wikstrand, John, Wienhues-Thelen, Ursula-Henrike, Block, Dirk, Zaugg, Christian, Gullestad, Lars
• Format: Journal Article
• Language: English
• Published: Basel, Switzerland S. Karger AG 01.01.2015
• Subjects: Aged; Aged, 80 and over; C-Reactive Protein - metabolism; Cardiology; Endostatins - blood; Female; Fluorobenzenes - therapeutic use; Glomerular Filtration Rate - physiology; Heart failure; Heart Failure, Systolic - blood; Heart Failure, Systolic - drug therapy; Heart Failure, Systolic - mortality; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors - therapeutic use; Immunoenzyme Techniques; Kidney Diseases - blood; Kidney Diseases - drug therapy; Kidney Diseases - mortality; Kidneys; Male; Medical prognosis; Middle Aged; Natriuretic Peptide, Brain - blood; Original Research; Pyrimidines - therapeutic use; Rosuvastatin Calcium; Statins; Sulfonamides - therapeutic use; Heart failure; Prognosis; Kidney function; Survival; Endostatin

Objectives: Increased circulating endostatin levels have been demonstrated in progressive cardiovascular (CV) and renal disorders. We investigated the predictive value of endostatin in patients with chronic heart failure (HF) and the association between endostatin and renal function. Methods: The in...