Efficacy of drugs treatment in patients with endometrial hyperplasia with or without atypia: A systematic review and network meta-analysis

• Published in: Medicine (Baltimore) Vol. 103; no. 38; p. e39619
• Main Authors: Yao, Yingsha, Xu, Shuhang, Wang, Ting, Jiang, Ruoan
• Format: Journal Article
• Language: English
• Published: Hagerstown, MD Lippincott Williams & Wilkins 20.09.2024
• Subjects: Endometrial Hyperplasia - drug therapy; Endometrial Hyperplasia - pathology; Female; Humans; Levonorgestrel - administration & dosage; Levonorgestrel - therapeutic use; Medroxyprogesterone Acetate - administration & dosage; Medroxyprogesterone Acetate - therapeutic use; Metformin - therapeutic use; Randomized Controlled Trials as Topic; Systematic Review and Meta-Analysis; treatment; network meta-analysis; endometrial hyperplasia; management

Background: Endometrial hyperplasia (EH) is a hyperplastic endometrial lesion with irregular gland size, increased glands, and increased glandular interstitial ratio. During follow-up, some EH progressed further to endometrial cancer. It is crucial to provide timely treatment for EH and improve the...