Effect of physical activity on functional performance and knee pain in patients with osteoarthritis : analysis with marginal structural models

• Published in: Epidemiology (Cambridge, Mass.) Vol. 23; no. 4; p. 631
• Main Authors: Mansournia, Mohammad Ali, Danaei, Goodarz, Forouzanfar, Mohammad Hossein, Mahmoodi, Mahmood, Jamali, Mohsen, Mansournia, Nasrin, Mohammad, Kazem
• Format: Journal Article
• Language: English
• Published: United States 01.07.2012
• Subjects: Aged; Causality; Confounding Factors (Epidemiology); Exercise; Exercise Test; Female; Follow-Up Studies; Housekeeping; Humans; Leisure Activities; Male; Middle Aged; Models, Statistical; Osteoarthritis, Knee - physiopathology; Pain Measurement; Prospective Studies; Self Report; Treatment Outcome; Walking; Work

A previous analysis of the Osteoarthritis Initiative study reported a dose-response relationship between physical activity and improved physical function in adults with knee osteoarthritis, using conventional statistical methods. These methods are subject to bias when confounders are affected by pri...