Dopamine and memory function in Parkinson's disease

• Published in: Movement disorders Vol. 4; no. 2; p. 113
• Main Authors: Mohr, E, Fabbrini, G, Williams, J, Schlegel, J, Cox, C, Fedio, P, Chase, T N
• Format: Journal Article
• Language: English
• Published: United States 1989
• Subjects: Aged; Attention - physiology; Brain - physiopathology; Carbidopa - administration & dosage; Dopamine - physiology; Drug Combinations - administration & dosage; Female; Humans; Levodopa - administration & dosage; Male; Memory - physiology; Mental Recall - physiology; Middle Aged; Motor Skills - physiology; Neuropsychological Tests; Parkinson Disease - drug therapy; Parkinson Disease - physiopathology; Pattern Recognition, Visual - physiology; Receptors, Dopamine - physiology; Synaptic Transmission - drug effects; Verbal Learning - physiology

Response fluctuations in motor function, complicating long-term dopaminomimetic therapy of Parkinson's disease, may extend to the cognitive realm. To evaluate the effect of levodopa treatment both on attention as well as acquisition and retrieval of memory tasks, parkinsonian patients were exam...