Three-dimensional ultrashort echo time cones (3D UTE-Cones) magnetic resonance imaging of entheses and tendons

We present three-dimensional ultrashort echo time Cones (3D-UTE-Cones) imaging as well as quantification of T2* and magnetization transfer ratio (MTR) of Achilles tendon and its enthesis of healthy volunteers and patients with psoriatic arthritis (PsA) using a 3T scanner. Quantitative T2*, T2 and ma...

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Published inMagnetic resonance imaging Vol. 49; pp. 4 - 9
Main Authors Chen, Bimin, Zhao, Yinghua, Cheng, Xin, Ma, Yajun, Chang, Eric Y., Kavanaugh, Arthur, Liu, Sirun, Du, Jiang
Format Journal Article
LanguageEnglish
Published Netherlands Elsevier Inc 01.06.2018
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Abstract We present three-dimensional ultrashort echo time Cones (3D-UTE-Cones) imaging as well as quantification of T2* and magnetization transfer ratio (MTR) of Achilles tendon and its enthesis of healthy volunteers and patients with psoriatic arthritis (PsA) using a 3T scanner. Quantitative T2*, T2 and magnetization transfer ratio (MTR) measurements of Achilles tendon and its enthesis were performed on healthy volunteers (n=7) and PsA patients (n=9) with 3D-UTE-Cones and clinical sequences at 3T. T2* was measured via single-component fitting of UTE images from two interleaved dual echo 3D-UTE-Cones acquisitions. MTR was measured with a dual echo 3D-UTE-Cones-MT sequence. Clinical morphological imaging and quantification of T2 with a Carr-Purcell-Meiboom-Gill (CPMG) sequence and MTR with a gradient recalled echo (GRE) sequence were also performed on each subject. T2* and MTR were analyzed for the two groups and the significance was evaluated. The 3D-UTE-Cones sequence provided high resolution imaging of entheses and tendons. Cones-T2* and Cones-MTR values were significantly higher for the PsA patients. GRE-MTR values showed no significant differences between the groups. No reliable T2 measurement could be achieved with the CPMG sequence due to insufficient signal from entheses and tendons. The 3D-UTE-Cones sequences can be used for morphological and quantitative evaluation of entheses and tendons in PsA patients.
AbstractList We present three-dimensional ultrashort echo time Cones (3D-UTE-Cones) imaging as well as quantification of T2* and magnetization transfer ratio (MTR) of Achilles tendon and its enthesis of healthy volunteers and patients with psoriatic arthritis (PsA) using a 3T scanner. Quantitative T2*, T2 and magnetization transfer ratio (MTR) measurements of Achilles tendon and its enthesis were performed on healthy volunteers (n=7) and PsA patients (n=9) with 3D-UTE-Cones and clinical sequences at 3T. T2* was measured via single-component fitting of UTE images from two interleaved dual echo 3D-UTE-Cones acquisitions. MTR was measured with a dual echo 3D-UTE-Cones-MT sequence. Clinical morphological imaging and quantification of T2 with a Carr-Purcell-Meiboom-Gill (CPMG) sequence and MTR with a gradient recalled echo (GRE) sequence were also performed on each subject. T2* and MTR were analyzed for the two groups and the significance was evaluated. The 3D-UTE-Cones sequence provided high resolution imaging of entheses and tendons. Cones-T2* and Cones-MTR values were significantly higher for the PsA patients. GRE-MTR values showed no significant differences between the groups. No reliable T2 measurement could be achieved with the CPMG sequence due to insufficient signal from entheses and tendons. The 3D-UTE-Cones sequences can be used for morphological and quantitative evaluation of entheses and tendons in PsA patients.
We present three-dimensional ultrashort echo time Cones (3D-UTE-Cones) imaging as well as quantification of T2* and magnetization transfer ratio (MTR) of Achilles tendon and its enthesis of healthy volunteers and patients with psoriatic arthritis (PsA) using a 3T scanner. Quantitative T2*, T2 and magnetization transfer ratio (MTR) measurements of Achilles tendon and its enthesis were performed on healthy volunteers (n=7) and PsA patients (n=9) with 3D-UTE-Cones and clinical sequences at 3T. T2* was measured via single-component fitting of UTE images from two interleaved dual echo 3D-UTE-Cones acquisitions. MTR was measured with a dual echo 3D-UTE-Cones-MT sequence. Clinical morphological imaging and quantification of T2 with a Carr-Purcell-Meiboom-Gill (CPMG) sequence and MTR with a gradient recalled echo (GRE) sequence were also performed on each subject. T2* and MTR were analyzed for the two groups and the significance was evaluated. The 3D-UTE-Cones sequence provided high resolution imaging of entheses and tendons. Cones-T2* and Cones-MTR values were significantly higher for the PsA patients. GRE-MTR values showed no significant differences between the groups. No reliable T2 measurement could be achieved with the CPMG sequence due to insufficient signal from entheses and tendons. The 3D-UTE-Cones sequences can be used for morphological and quantitative evaluation of entheses and tendons in PsA patients.We present three-dimensional ultrashort echo time Cones (3D-UTE-Cones) imaging as well as quantification of T2* and magnetization transfer ratio (MTR) of Achilles tendon and its enthesis of healthy volunteers and patients with psoriatic arthritis (PsA) using a 3T scanner. Quantitative T2*, T2 and magnetization transfer ratio (MTR) measurements of Achilles tendon and its enthesis were performed on healthy volunteers (n=7) and PsA patients (n=9) with 3D-UTE-Cones and clinical sequences at 3T. T2* was measured via single-component fitting of UTE images from two interleaved dual echo 3D-UTE-Cones acquisitions. MTR was measured with a dual echo 3D-UTE-Cones-MT sequence. Clinical morphological imaging and quantification of T2 with a Carr-Purcell-Meiboom-Gill (CPMG) sequence and MTR with a gradient recalled echo (GRE) sequence were also performed on each subject. T2* and MTR were analyzed for the two groups and the significance was evaluated. The 3D-UTE-Cones sequence provided high resolution imaging of entheses and tendons. Cones-T2* and Cones-MTR values were significantly higher for the PsA patients. GRE-MTR values showed no significant differences between the groups. No reliable T2 measurement could be achieved with the CPMG sequence due to insufficient signal from entheses and tendons. The 3D-UTE-Cones sequences can be used for morphological and quantitative evaluation of entheses and tendons in PsA patients.
Author Liu, Sirun
Zhao, Yinghua
Cheng, Xin
Chen, Bimin
Ma, Yajun
Kavanaugh, Arthur
Chang, Eric Y.
Du, Jiang
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Keywords MTR
Cones
Enthesis
T2
UTE
Tendon
Language English
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Snippet We present three-dimensional ultrashort echo time Cones (3D-UTE-Cones) imaging as well as quantification of T2* and magnetization transfer ratio (MTR) of...
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SubjectTerms Achilles Tendon - diagnostic imaging
Achilles Tendon - pathology
Adult
Arthritis, Psoriatic - diagnostic imaging
Arthritis, Psoriatic - pathology
Cones
Enthesis
Female
Humans
Image Processing, Computer-Assisted - methods
Imaging, Three-Dimensional - methods
Magnetic Resonance Imaging - methods
Male
MTR
Tendon
UTE
Title Three-dimensional ultrashort echo time cones (3D UTE-Cones) magnetic resonance imaging of entheses and tendons
URI https://www.clinicalkey.com/#!/content/1-s2.0-S0730725X17303028
https://dx.doi.org/10.1016/j.mri.2017.12.034
https://www.ncbi.nlm.nih.gov/pubmed/29309823
https://www.proquest.com/docview/1989554856
Volume 49
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