Hyaluronic acid as an internal wetting agent in model DMAA/TRIS contact lenses

• Published in: Journal of biomaterials applications Vol. 27; no. 4; p. 423
• Main Authors: Weeks, Andrea, Luensmann, Doerte, Boone, Adrienne, Jones, Lyndon, Sheardown, Heather
• Format: Journal Article
• Language: English
• Published: England 01.11.2012
• Subjects: Acrylamides - chemistry; Adsorption; Animals; Chickens; Contact Lenses, Hydrophilic; Hyaluronic Acid - chemistry; Hydrophobic and Hydrophilic Interactions; Muramidase - chemistry; Photoelectron Spectroscopy; Protein Denaturation; Silanes - chemistry; Water - chemistry; Wetting Agents - chemistry

Model silicone hydrogel contact lenses, comprised of N,N-dimethylacrylamide and methacryloxypropyltris (trimethylsiloxy) silane, were fabricated and hyaluronic acid (HA) was incorporated as an internal wetting agent using a dendrimer-based method. HA and dendrimers were loaded into the silicone hydr...