ESTIMATION OF CELL LINEAGE TREES BY MAXIMUM-LIKELIHOOD PHYLOGENETICS

CRISPR technology has enabled cell lineage tracing for complex multicellular organisms through insertion-deletion mutations of synthetic genomic barcodes during organismal development. To reconstruct the cell lineage tree from the mutated barcodes, current approaches apply general-purpose computatio...

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Bibliographic Details
Published inThe annals of applied statistics Vol. 15; no. 1; p. 343
Main Authors Feng, Jean, Dewitt, 3rd, William S, McKenna, Aaron, Simon, Noah, Willis, Amy D, Matsen, 4th, Frederick A
Format Journal Article
LanguageEnglish
Published United States 01.03.2021
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