Full structure building and docking of NifS from extremophile Acidithiobacillus ferrooxidans

• Published in: Transactions of Nonferrous Metals Society of China Vol. 18; no. 4; pp. 995 - 1002
• Main Author: 刘元东 邱冠周 王海东 蒋莹 张成桂 夏乐先
• Format: Journal Article
• Language: English
• Published: Elsevier Ltd 01.08.2008; School of Minerals Processing and Bioengineering, Central South University, Changsha 410083, China
• Subjects: Acidithiobacillus ferrooxidans; bioleaching; cysteine; docking; homology modeling; molecular dynamics; NifS; pyridoxal 5′-phosphate(PLP); 分子动力学; 半胱氨酸; 固氮基因; 固氮酶; Acidithiobacillus ferrooxidans; docking; pyridoxal 5′-phosphate(PLP); homology modeling; cysteine; bioleaching; molecular dynamics; NifS

The gene iscS-2 from extremophile Acidithiobacillus ferrooxidans may play a crucial role in nitrogenase maturation. To investigate the protein encoded by this gene, a reliable integral three-dimensional molecular structure was built. The obtained structure was further used to search binding sites, c...