EXIT from TRansrectal prostate biopsies (TREXIT): sepsis rates of transrectal biopsy with rectal swab culture guided antimicrobials versus freehand transperineal biopsy

• Published in: Prostate cancer and prostatic diseases Vol. 25; no. 2; pp. 283 - 287
• Main Authors: Newman, Thomas Hedley, Stroman, Luke, Hadjipavlou, Marios, Haque, Arman, Rusere, Jonah, Chan, Kimberley, Ioannides, Demetris, Di Benedetto, Antonina, Pinczes, Tibor, Popert, Rick, Hammadeh, Mohamed Y.
• Format: Journal Article
• Language: English
• Published: London Nature Publishing Group UK 01.02.2022; Nature Publishing Group
• Subjects: 692/699/2768/1753; 692/699/67/589/466; Anti-Infective Agents - therapeutic use; Antibiotic Prophylaxis - methods; Antiinfectives and antibacterials; Antimicrobial agents; Biomedical and Life Sciences; Biomedicine; Biopsy; Biopsy - adverse effects; Biopsy - methods; Cancer Research; Disease prevention; Empirical analysis; Humans; Image-Guided Biopsy - adverse effects; Longitudinal Studies; Male; Prophylaxis; Prostate; Prostate - pathology; Prostatic Neoplasms - diagnosis; Prostatic Neoplasms - pathology; Rectum; Rectum - pathology; Rectum - surgery; Reproductive Medicine; Risk; Sepsis; Sepsis - diagnosis; Sepsis - epidemiology; Sepsis - etiology; Switching

Background Transrectal prostate biopsy (TRUSBx) holds a risk of prostate biopsy related sepsis. We discuss our step-wise strategies aiming to reduce this risk, including targeted antimicrobials and switching to a freehand transperineal approach (FHTPBx). Subjects and methods This longitudinal cohort...