CD8+ T cells of chronic HCV-infected patients express multiple negative immune checkpoints following stimulation with HCV peptides
•HCV peptide-specific CD4+ and CD8+ T cells are key to successful viral clearance in HCV disease.•HCV peptide-specific T cells of chronic HCV patients had significant increase of CTLA-4.•The levels of IL-2, IL-17A and IL-6 were decreased in the T cell cultures of chronic HCV patients.•Chronic HCV di...
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Published in | Cellular immunology Vol. 313; pp. 1 - 9 |
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Main Authors | , , , , , , , , , , , |
Format | Journal Article |
Language | English |
Published |
Netherlands
Elsevier Inc
01.03.2017
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Subjects | |
Online Access | Get full text |
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