Effect of Helicobacter pylori eradication and high-density lipoprotein on the risk of de novo gastric cancer development

• Published in: Gastrointestinal endoscopy Vol. 90; no. 3; pp. 448 - 456.e1
• Main Authors: Nam, Su Youn, Park, Bum Joon, Nam, Ji Hyung, Kook, Myeong-Cherl
• Format: Journal Article
• Language: English
• Published: United States Elsevier Inc 01.09.2019
• Subjects: Adult; Antacids - therapeutic use; Anti-Bacterial Agents - therapeutic use; Cohort Studies; Female; Helicobacter Infections - drug therapy; Helicobacter Infections - epidemiology; Helicobacter pylori; Humans; Incidence; Lipoproteins, HDL - blood; Male; Middle Aged; Proportional Hazards Models; Protective Factors; Proton Pump Inhibitors - therapeutic use; Republic of Korea - epidemiology; Retrospective Studies; Risk Factors; Stomach Neoplasms - epidemiology; Treatment Failure; Republic of Korea; EGC; HDL; RCT; LDL; CI; HR; AGC; BMI

The effect of Helicobacter pylori eradication on de novo gastric cancer is controversial, although meta-analyses suggest a reduction in gastric cancer after eradication. The effect of high-density lipoprotein (HDL) on gastric cancer has been rarely reported. In this large retrospective cohort study,...