Bariatric Surgery: A Potential Treatment for Type 2 Diabetes in Youth

Type 2 diabetes, once referred to as "adult-onset" diabetes, has now emerged as a formidable threat to the health of obese adolescents. Although there is growing evidence regarding the epidemiology of type 2 diabetes in youth and its multisystem health consequences, treatment options have...

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Published inDiabetes care Vol. 39; no. 6; pp. 934 - 940
Main Authors Shah, Amy S, D'Alessio, David, Ford-Adams, Martha E, Desai, Ashish P, Inge, Thomas H
Format Journal Article
LanguageEnglish
Published United States American Diabetes Association 01.06.2016
Subjects
Adolescent
Adult
Age of Onset
Bariatric Surgery - methods
Bariatric Surgery - statistics & numerical data
Childrens health
Diabetes
Diabetes Mellitus, Type 2 - complications
Diabetes Mellitus, Type 2 - epidemiology
Diabetes Mellitus, Type 2 - surgery
Epidemiology
Gastrointestinal surgery
Humans
Metabolic Surgery and the Changing Landscape for Diabetes Care
Obesity
Pediatric Obesity - complications
Pediatric Obesity - epidemiology
Pediatric Obesity - surgery
Remission Induction
Teenagers
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Abstract Type 2 diabetes, once referred to as "adult-onset" diabetes, has now emerged as a formidable threat to the health of obese adolescents. Although there is growing evidence regarding the epidemiology of type 2 diabetes in youth and its multisystem health consequences, treatment options have lagged and progression of disease occurs even with aggressive medical therapy. Increasing interest in the application of bariatric surgery for adolescents with type 2 diabetes has evolved in part because of the evidence demonstrating improvement or remission in many adults with diabetes after surgery. Here, we review the burden of type 2 diabetes in youth including its associated complications, discuss the outcomes and complications of bariatric surgery in adolescents with diabetes, and conclude with recommendations for future research and options for refinement of the use of bariatric surgery in this patient population.
AbstractList Type 2 diabetes, once referred to as "adult-onset" diabetes, has now emerged as a formidable threat to the health of obese adolescents. Although there is growing evidence regarding the epidemiology of type 2 diabetes in youth and its multisystem health consequences, treatment options have lagged and progression of disease occurs even with aggressive medical therapy. Increasing interest in the application of bariatric surgery for adolescents with type 2 diabetes has evolved in part because of the evidence demonstrating improvement or remission in many adults with diabetes after surgery. Here, we review the burden of type 2 diabetes in youth including its associated complications, discuss the outcomes and complications of bariatric surgery in adolescents with diabetes, and conclude with recommendations for future research and options for refinement of the use of bariatric surgery in this patient population.
Author Shah, Amy S
D'Alessio, David
Desai, Ashish P
Inge, Thomas H
Ford-Adams, Martha E
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  organization: Division of Endocrinology, Metabolism, and Nutrition, Department of Medicine, Duke University School of Medicine, Durham, NC Durham VA Medical Center, Durham, NC
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  givenname: Martha E
  surname: Ford-Adams
  fullname: Ford-Adams, Martha E
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  givenname: Ashish P
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  fullname: Desai, Ashish P
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  givenname: Thomas H
  surname: Inge
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  organization: Department of Surgery, Cincinnati Children's Hospital and University of Cincinnati, Cincinnati, OH thomas.inge@cchmc.org
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Copyright 2016 by the American Diabetes Association. Readers may use this article as long as the work is properly cited, the use is educational and not for profit, and the work is not altered.
Copyright American Diabetes Association Jun 1, 2016
2016 by the American Diabetes Association. Readers may use this article as long as the work is properly cited, the use is educational and not for profit, and the work is not altered. 2016
Copyright_xml – notice: 2016 by the American Diabetes Association. Readers may use this article as long as the work is properly cited, the use is educational and not for profit, and the work is not altered.
– notice: Copyright American Diabetes Association Jun 1, 2016
– notice: 2016 by the American Diabetes Association. Readers may use this article as long as the work is properly cited, the use is educational and not for profit, and the work is not altered. 2016
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Snippet Type 2 diabetes, once referred to as "adult-onset" diabetes, has now emerged as a formidable threat to the health of obese adolescents. Although there is...
Type 2 diabetes, once referred to as “adult-onset” diabetes, has now emerged as a formidable threat to the health of obese adolescents. Although there is...
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SubjectTerms Adolescent
Adult
Age of Onset
Bariatric Surgery - methods
Bariatric Surgery - statistics & numerical data
Childrens health
Diabetes
Diabetes Mellitus, Type 2 - complications
Diabetes Mellitus, Type 2 - epidemiology
Diabetes Mellitus, Type 2 - surgery
Epidemiology
Gastrointestinal surgery
Humans
Metabolic Surgery and the Changing Landscape for Diabetes Care
Obesity
Pediatric Obesity - complications
Pediatric Obesity - epidemiology
Pediatric Obesity - surgery
Remission Induction
Teenagers
Title Bariatric Surgery: A Potential Treatment for Type 2 Diabetes in Youth
URI https://www.ncbi.nlm.nih.gov/pubmed/27222551
https://www.proquest.com/docview/1794947560/abstract/
https://search.proquest.com/docview/1791720001
https://pubmed.ncbi.nlm.nih.gov/PMC5317244
Volume 39
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